Protein Alignment Rab5 and RAB27A

DIOPT Version :9

• Sequence 1: NP_001259925.1
• Gene: Rab5 / 33418
• FlyBaseID: FBgn0014010
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_004571.2
• Gene: RAB27A / 5873
• HGNCID: 9766
• Length: 221
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 55/163 - (33%)
• Similarity: 95/163 - (58%)
• Gaps: 15/163 - (9%)

  Fly    31 KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDT----------VVKFEIWDT 85
            |.:.||:|.|||:|::.::..|:|:....:|:|..|..:.:....:          .:..::|||
Human    11 KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHLQLWDT 75

  Fly    86 AGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQA---SPNIVIALAGNKADLS 147
            |||||:.||...::|.|...::::|:.|:.||...:.|:.:|...|   :|:||  |.|||:||.
Human    76 AGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIV--LCGNKSDLE 138

  Fly   148 NIRVVEFDEAKQYAEENGLLFMETSAKTGMNVN 180
            :.|||:.:||...||:.|:.:.||||..|.|::
Human   139 DQRVVKEEEAIALAEKYGIPYFETSAANGTNIS 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	55/163 (34%)
RAB27A	NP_004571.2	Rab27A	6..185	CDD:206700	55/163 (34%)
		Effector region. /evidence=ECO:0000250	38..46		2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910