Protein Alignment Rab5 and RAB23

DIOPT Version :10

• Sequence 1: NP_523457.1
• Gene: Rab5 / 33418
• FlyBaseID: FBgn0014010
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_057361.3
• Gene: RAB23 / 51715
• HGNCID: 14263
• Length: 237
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 72/225 - (32%)
• Similarity: 116/225 - (51%)
• Gaps: 39/225 - (17%)

  Fly    31 KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIWDTAGQERYHSLA 95
            |:|::|..||||||::.|:.||.|.:..:.|||..||.:.|.:.|..|:..:|||||||.:.::.
Human    11 KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAIT 75

  Fly    96 PMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIVIALAGNKADLSNIRVVEFDEAKQY 160
            ..|||||||.::|:...:::||:...:|.:::..:.. :|...|..||.||.:...::.:||:..
Human    76 KAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVG-DIPTVLVQNKIDLLDDSCIKNEEAEAL 139

  Fly   161 AEENGLLFMETSAKTGMNVNDIFLAIAKK-LPK-------------------------------- 192
            |:...|.|..||.|..:|||::|..:|:| |.|
Human   140 AKRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQKLKQQIAEDPELTHSSSNKIGVFNTSGGSHSGQ 204

  Fly   193 NDGANNQG--TSIRPT--GTETNR-PTNNC 217
            |.|..|.|  .::||.  .|:.|| |.::|
Human   205 NSGTLNGGDVINLRPNKQRTKKNRNPFSSC 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_523457.1	Rab5_related	29..191	CDD:206653	59/160 (37%)
RAB23	NP_057361.3	Rab23_like	10..169	CDD:133306	58/158 (37%)