DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab5 and Rab7b

DIOPT Version :9

Sequence 1:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001102798.1	Gene:	Rab7b / 501854	RGDID:	1562617	Length:	199	Species:	Rattus norvegicus

Alignment Length:	202	Identity:	64/202 - (31%)
Similarity:	113/202 - (55%)	Gaps:	16/202 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIWDTAGQER 90
            |....||:::|...|||:||:.::|...|.|..::|:||:.|::.|.::||.:|.:||||.||||
  Rat     5 KKVDLKLIIVGALGVGKTSLLHQYVHKTFFEEYQTTLGASILSKIIILDDTTLKLQIWDTGGQER 69

  Fly    91 YHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKEL------HKQASPNIVIALAGNKADLSNI 149
            :.|:...:|:|:...|:.:|:.:.:||:....|..::      .:|:.|.:|:   |||.||.:
  Rat    70 FRSMVSTFYKGSDGCILAFDVTDPESFEALDIWRDDVLAKIVPMEQSYPMVVL---GNKIDLED- 130

  Fly   150 RVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKK-LPKNDG--ANNQGTSIRPTGTETN 211
            |.|..:.|.::.:|..:.:.|.|||..:||...|..:|.: |.:..|  .|:...||:   ....
  Rat   131 RKVPQEVAHEWCKEKDMPYFEVSAKNDINVVQAFEVLASRALLRYQGIAENHLADSIK---LSPG 192

  Fly   212 RPTNNCC 218
            :|.:.||
  Rat   193 QPRSKCC 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	55/168 (33%)
Rab7b	NP_001102798.1	Rab	9..169	CDD:206640	54/163 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910