DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab5 and kras

DIOPT Version :9

Sequence 1:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001008034.1	Gene:	kras / 493396	XenbaseID:	XB-GENE-6036229	Length:	186	Species:	Xenopus tropicalis

Alignment Length:	166	Identity:	52/166 - (31%)
Similarity:	97/166 - (58%)	Gaps:	3/166 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIWDTAGQERYHS 93
            ::|||::|...||||:|.::.::..|.:..:.||..::..|.: |:......:|.||||||.|.:
Frog     3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVV-IDGETCLLDILDTAGQEEYSA 66

  Fly    94 LAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHK-QASPNIVIALAGNKADLSNIRVVEFDEA 157
            :...|.|..:..:.|:.|.|..||:....:.::::: :.|.::.:.|.|||.||.: |.|:..:|
Frog    67 MRDQYMRTGEGFLCVFAINNTKSFEDVHHYREQINRVKDSDDVPMVLVGNKCDLPS-RTVDTKQA 130

  Fly   158 KQYAEENGLLFMETSAKTGMNVNDIFLAIAKKLPKN 193
            ::.|:..|:.|:||||||...|.|.|..:.:::.|:
Frog   131 QELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRKH 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	51/162 (31%)
kras	NP_001008034.1	H_N_K_Ras_like	3..164	CDD:133338	51/162 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910