Protein Alignment Rab5 and RRAS2

DIOPT Version :9

• Sequence 1: NP_001259925.1
• Gene: Rab5 / 33418
• FlyBaseID: FBgn0014010
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_036382.2
• Gene: RRAS2 / 22800
• HGNCID: 17271
• Length: 204
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 59/205 - (28%)
• Similarity: 109/205 - (53%)
• Gaps: 18/205 - (8%)

  Fly    20 NGTSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIWD 84
            :|:.|.|   ::||::|...||||:|.::|::..|....:.||..::..|.: |:|...:.:|.|
Human     8 DGSGQEK---YRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCV-IDDRAARLDILD 68

  Fly    85 TAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKEL----HKQASPNIVIALAGNKAD 145
            |||||.:.::...|.|..:..::|:.:.::.||:....:.:::    .:...|.|:|   |||||
Human    69 TAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILI---GNKAD 130

  Fly   146 LSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIF---LAIAKKLPKNDGANNQGTSIRPTG 207
            |.:.|.|..:|.:|.|.:..:.:||.|||..|||:..|   :.:.:|..:.:..    .|..||.
Human   131 LDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECP----PSPEPTR 191

  Fly   208 TETNRPTNNC 217
            .|.::...:|
Human   192 KEKDKKGCHC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	51/168 (30%)
RRAS2	NP_036382.2	M_R_Ras_like	13..176	CDD:133345	51/169 (30%)
		Effector region	43..51		2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910