DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab5 and Dnajc27

DIOPT Version :9

Sequence 1:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	XP_006515115.1	Gene:	Dnajc27 / 217378	MGIID:	2443036	Length:	298	Species:	Mus musculus

Alignment Length:	226	Identity:	61/226 - (26%)
Similarity:	102/226 - (45%)	Gaps:	42/226 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PNGTSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVKFEIW 83
            |......||.:.|::.:|.:.||||.::.|:.:.:|.....:|||..:....:.:.|..:|..|:
Mouse     6 PKRKEPAKSLRIKVISMGNAEVGKSCIIKRYCEKRFVSKYLATIGIDYGVTKVQVRDREIKVNIF 70

  Fly    84 DTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASP-----NIVIALAGNK 143
            |.||...:..:...:|:..|..|:|||:..:|||....:|:.|:.::..|     |||..:..||
Mouse    71 DMAGHPFFFEVRNEFYKDTQGVILVYDVGQKDSFDALDSWLAEMKQELGPHGNMDNIVFVVCANK 135

  Fly   144 A-------------------------DLSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIF 183
            .                         |.|..|.::..|.:.:||..|.|:.||||:||..:|::|
Mouse   136 GRDLTWPGVVGQGGFSLCPALTLFQIDCSKHRCIDESEGRLWAESKGFLYFETSAQTGEGINEMF 200

  Fly   184 ----LAIAKKLPKNDGANNQGTSIRPTGTET 210
                |:|.      |...|.|.  |||.:.:
Mouse   201 QTFYLSIV------DLCENGGK--RPTASSS 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	52/195 (27%)
Dnajc27	XP_006515115.1	RJL	17..209	CDD:133319	52/197 (26%)
Dnajc27	XP_006515115.1	DnaJ	242..289	CDD:99751
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910