DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab5 and drn-1

DIOPT Version :9

Sequence 1:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001333544.2	Gene:	drn-1 / 183765	WormBaseID:	WBGene00016911	Length:	219	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	57/202 - (28%)
Similarity:	95/202 - (47%)	Gaps:	14/202 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SGTGTAQRPNGTSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIED 75
            :.|.||...:..::..:..:::.:.|...|||||:..|||||.|:|....||...:.....|.:.
Worm    12 AATTTAGSGSKVAEASTSDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQK 76

  Fly    76 TVVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIV---- 136
            .|...:|.||.|..::.::..:......|.|::|.:.|:.||..... :.|:.|:...|.:
Worm    77 NVCTLQITDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVP-IIEMMKEVKGNAIAETP 140

  Fly   137 IALAGNKADLSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIF---LAIAKK------LPK 192
            |.|.|||.|..:.|.|..:..::.|......|:|||||...|:.::|   ||:.||      :..
Worm   141 IMLVGNKKDEESKREVSSNSGQKVATNMECGFIETSAKNNENITELFQQLLALEKKRQLALTMDD 205

  Fly   193 NDGANNQ 199
            .||.|.:
Worm   206 PDGKNGK 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	51/174 (29%)
drn-1	NP_001333544.2	P-loop_NTPase	30..195	CDD:328724	49/165 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910