DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab5 and rab39a

DIOPT Version :9

Sequence 1:NP_001259925.1 Gene:Rab5 / 33418 FlyBaseID:FBgn0014010 Length:219 Species:Drosophila melanogaster
Sequence 2:XP_002934692.1 Gene:rab39a / 100494491 XenbaseID:XB-GENE-1011717 Length:206 Species:Xenopus tropicalis


Alignment Length:169 Identity:63/169 - (37%)
Similarity:96/169 - (56%) Gaps:12/169 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIED-----TVVKFEIWDTAGQ 88
            ||:::|||:|.|||:||:.|:..|||.:....|:|..|    .|.|:     ..|:.:.||||||
 Frog     8 QFRVLLLGDSGVGKTSLLHRYTDGQFTDTTTETVGVDF----CCREEEPEPGVKVRLQFWDTAGQ 68

  Fly    89 ERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKEL--HKQASPNIVIALAGNKADLSNIRV 151
            |||.::...|||.|...::::|:..:.||.....|..|:  ..||.| :|..|.|.|.||...|:
 Frog    69 ERYRAVTRSYYRNAAGVLLLFDLTTRQSFDNVTEWHMEVTERTQAKP-MVFMLLGAKNDLKEKRM 132

  Fly   152 VEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKL 190
            |..:||::.||.....::||||:||.||:.....:.::|
 Frog   133 VTREEAQRLAENLSAPYLETSARTGSNVSAALSLLCREL 171

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab5NP_001259925.1 Rab5_related 29..191 CDD:206653 63/169 (37%)
rab39aXP_002934692.1 P-loop_NTPase 7..>171 CDD:393306 62/167 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1340129at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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