DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab5 and Rab5al1

DIOPT Version :9

Sequence 1:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	XP_003751425.1	Gene:	Rab5al1 / 100361891	RGDID:	2319287	Length:	215	Species:	Rattus norvegicus

Alignment Length:	208	Identity:	154/208 - (74%)
Similarity:	173/208 - (83%)	Gaps:	5/208 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQRPNG-TSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIEDTVVK 79
            |.|||| .:.||.|||||||||||||||||||||||||||||:|||||||||||||:|::||.||
  Rat     6 ATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVK 70

  Fly    80 FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIVIALAGNKA 144
            ||||||||||||||||||||||||||||||||.|::||.|||.|||||.:||||||||||:||||
  Rat    71 FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPNIVIALSGNKA 135

  Fly   145 DLSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKLPKNDGANNQGTSIRPTGTE 209
            ||:|.|.|:|.||:.||::|.||||||||||.||||:||:|||||||||:..|....|.|..|.:
  Rat   136 DLANKRAVDFQEAQSYADDNSLLFMETSAKTPMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVD 200

  Fly   210 TNRPT----NNCC 218
            ...|.    :.||
  Rat   201 LTEPAQPARSQCC 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	135/161 (84%)
Rab5al1	XP_003751425.1	Rab5_related	20..182	CDD:206653	135/161 (84%)
Rab5al1	XP_003751425.1	Ras	22..183	CDD:278499	134/160 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I1654
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	308	1.000	Inparanoid score	I2540
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340129at2759
OrthoFinder	1	1.000	-	-		FOG0000845
OrthoInspector	1	1.000	-	-		otm45820
orthoMCL	1	0.900	-	-		OOG6_100743
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X457
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870