DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9967 and MKRN2OS

DIOPT Version :9

Sequence 1:	NP_001014461.1	Gene:	CG9967 / 33414	FlyBaseID:	FBgn0031413	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_001182208.1	Gene:	MKRN2OS / 100129480	HGNCID:	40375	Length:	223	Species:	Homo sapiens

Alignment Length:	246	Identity:	71/246 - (28%)
Similarity:	112/246 - (45%)	Gaps:	51/246 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ILCFHHCNVKVFCFTLPHTCPHCNAPLDADVDAHGDVDGDADPSAQLDRAGPRLLLLPFRLPYPF 80
            ::.|:||...::.|::|..||.|...|.               |.:|:.|       |..:..||
Human    10 LIKFNHCEKYIYSFSVPQCCPLCQQDLG---------------SRKLEDA-------PVSIANPF 52

  Fly    81 VRATQHPCAIVLRPSAGDFLNDYSNATDLHIAVTTSGGDIVEFDRFGLRRHRRDDNPPEWRQSL- 144
            ....|..|:.:|||:.|.||.:|...:|||:.:|.:.|.:..:...|::|     :...|.:|:
Human    53 TNGHQEKCSFLLRPTQGTFLREYDGRSDLHVGITNTNGVVYNYSAHGVQR-----DGEGWEESIS 112

  Fly   145 -------MVGDVPEPWHDFWDEVLQQICAQSVRWSIASYAEESHNCYAFVLAF----LQALGHAH 198
                   |.|.:.:     ||:.|:.. :.|..|....|.:..||||::.|.|    |.|.|...
Human   113 IPLLQPNMYGMMEQ-----WDKYLEDF-STSGAWLPHRYEDNHHNCYSYALTFINCVLMAEGRQQ 171

  Fly   199 LSEAARSKTAFCEQCIVPRTTTAGKYISLYRKIRRSGIYVHRQQPKNRSKP 249
            |     .|..|.|:.:||||..|.|:|:|||.||..|.|| ...|:.:::|
Human   172 L-----DKGEFTEKYVVPRTRLASKFITLYRAIREHGFYV-TDCPQQQAQP 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9967	NP_001014461.1	DUF4796	14..231	CDD:292663	64/226 (28%)
MKRN2OS	NP_001182208.1	DUF4796	8..199	CDD:292663	64/226 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I7064
eggNOG	1	0.900	-	-		E1_2CJJG
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H66298
Inparanoid	1	1.050	109	1.000	Inparanoid score	I4912
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49162
OrthoDB	1	1.010	-	-		D1134473at2759
OrthoFinder	1	1.000	-	-		FOG0005520
OrthoInspector	1	1.000	-	-		oto90274
orthoMCL	1	0.900	-	-		OOG6_109257
Panther	1	1.100	-	-	LDO	PTHR33963
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3047
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870