DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17237 and MYL6B

DIOPT Version :9

Sequence 1:	NP_608666.1	Gene:	CG17237 / 33411	FlyBaseID:	FBgn0031410	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001186558.1	Gene:	MYL6B / 140465	HGNCID:	29823	Length:	208	Species:	Homo sapiens

Alignment Length:	188	Identity:	48/188 - (25%)
Similarity:	84/188 - (44%)	Gaps:	20/188 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PSSIRPSSTTPDCNQKRRGDMTAPPPNPKPE------KSRIMEMHAIFLGHDTRGDNKISIRHLG 69
            |:..:.....|...||     |..||....:      |.::.|....|...|..||.||.....|
Human    31 PAKTKAEPAVPQAPQK-----TQEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCG 90

  Fly    70 HCLRAMGATPTEAMVSKHVRQYEASTM--QRICFDEVMGIYSSLGKHGGMLSPKKKQIEADQFVS 132
            ..:||:|..||.|.|.|.:...::..:  :|:.|:..:.:..::.|:.|       |...:.::.
Human    91 DVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRG-------QGTYEDYLE 148

  Fly   133 SLRVFDTDKSGWIPAIRLRRILTKTGECMGSMEVDELLQGRINKDGLVDYKKLVQDII 190
            ..||||.:.:|.:....||.:||..||.|...||:.:|.|..:.:|.::|:..::.|:
Human   149 GFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHEDSNGCINYEAFLKHIL 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17237	NP_608666.1	PTZ00184	45..187	CDD:185504	39/143 (27%)
CG17237	NP_608666.1	EFh	129..187	CDD:298682	18/57 (32%)
MYL6B	NP_001186558.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51		5/24 (21%)
		PTZ00184	58..207	CDD:185504	41/156 (26%)
		EFh	68..132	CDD:298682	18/63 (29%)
		EFh	68..96	CDD:197492	9/27 (33%)
		EFh	150..205	CDD:238008	18/54 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0030
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23048
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910