DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4271 and tmprss5

DIOPT Version :9

Sequence 1:	NP_608665.1	Gene:	CG4271 / 33410	FlyBaseID:	FBgn0031409	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	246	Identity:	67/246 - (27%)
Similarity:	114/246 - (46%)	Gaps:	36/246 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 IYNGVEAKFDFWTFLASVWVSGYHECGGAVIDSRIVLTAAQCVKNKPVKR----------ITVRV 73
            |..||||....|.:..|::.:..|.|||::|.::.::|||.||.|..:.:          ||..:
Zfish   312 IIGGVEAALGRWPWQVSLYYNNRHICGGSIITNQWIVTAAHCVHNYRLPQVPSWVVYAGIITSNL 376

  Fly    74 GTPDIYRGGRIIRVTALVVHENY--KNWDNDIALLWLEKPVL---SVRVTKIPLATKEPSENEYP 133
            .....|:|..:.|:   :.::||  :..||||||:.|:.|:.   ::|...:|     ..:::.|
Zfish   377 AKLAQYQGFAVERI---IYNKNYNHRTHDNDIALVKLKTPLNFSDTIRPVCLP-----QYDHDLP 433

  Fly   134 SN-----AGWGEKLLESYVVTRKLQNGVTKIRPRSMCAEELV--EPVGEELLCAFYTEN--DICP 189
            ..     :|||....:..::...|:.....:.....|....:  ..:...:|||.|:|.  |.|.
Zfish   434 GGTQCWISGWGYTQPDDVLIPEVLKEAPVPLISTKKCNSSCMYNGEITSRMLCAGYSEGKVDACQ 498

  Fly   190 GDYGGPLVLAN----KVVGIAVQGHGCGFAVLPSLYTNVFHYLEWIEENAE 236
            ||.|||||..:    ::||:...|.||.....|.:|:.|..:|.||.:..|
Zfish   499 GDSGGPLVCQDENVWRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWIYDIIE 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4271	NP_608665.1	Tryp_SPc	19..234	CDD:238113	66/242 (27%)
CG4271	NP_608665.1	Tryp_SPc	19..231	CDD:214473	64/239 (27%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	64/239 (27%)
		Tryp_SPc	312..547	CDD:238113	66/242 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910