Protein Alignment CG4271 and Klk1b8

DIOPT Version :10

• Sequence 1: NP_608665.1
• Gene: CG4271 / 33410
• FlyBaseID: FBgn0031409
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_032483.1
• Gene: Klk1b8 / 16624
• MGIID: 892018
• Length: 261
• Species: Mus musculus
• Alignment Length: 541
• Identity: 105/541 - (19%)
• Similarity: 178/541 - (32%)
• Gaps: 144/541 - (26%)

  Fly    83 YAAWAEAGLFPVEDLMNLRKIDSDLEGHPTPRLNFIDVGTGSLGQGVAVACGMAYVGKNLDKAD- 146
            |...|||..|     ||..|.|:...|:     :..|.|...|.:..........:..|: |||
Mouse    92 YYKGAEAAYF-----MNQLKYDAMALGN-----HEFDNGVDGLLKPFLQEVNCTVLSANI-KADE 145

  Fly   147 ------------YRTYVLVGDGESAEGSIWESLHFAGYYKLNNLCVIFDVNRLG-QSEATSLQHQ 198
                        |:.:.|        ||  |.:...||.......:......|. :.|.|:||.|
Mouse   146 TLAPRISGYYFPYKIFTL--------GS--EKVGVVGYTSAETPALSLPGPHLKFEDEITALQPQ 200

  Fly   199 MEVYRKRLDAFGFNAIVVDGHD---VEELCKAFFEAAS------------TTDRPTA-------- 240
            ::    :|...|.|.|:..||.   ::::.....:...            |.|.|:.
Mouse   201 VD----KLLTLGVNKIIALGHSGFLMDQMIAKKVQGVDVVIGGHTNTFLYTGDPPSTEVPAGPYP 261

  Fly   241 IIAKTYKGKHFPNIEDLENWHGKPLG------DAAADVVAHLQKQIRNPG-PIAL-APPSPQKES 297
            ::.|:..|:..|.::...  .||.||      ||..:|       :.:.| ||.| :...|..:.
Mouse   262 LMVKSDDGRQVPVVQAYA--FGKYLGFLKVTFDANGNV-------LESTGNPILLNSSVEPDPDI 317

  Fly   298 APKVSIKGVELATPPAYQKGEQVATRLAYGT----ALAKIAMNN---DRVIALDGDTKNSTYSDK 355
            ..||....:.||...:.|.|:.:.  ...||    ...:..:.|   |.::     ..|..|:|:
Mouse   318 QAKVDSWRMNLANYSSQQVGQTLV--FLNGTFEECRFRECNLGNLICDAMV-----HHNIKYADE 375

  Fly   356 LRKAFPERFIECFIAEQNLVGVAIGAACRDRTVAFVSTFATF-FTRAFD--QIRMGAISQTNVNF 417
            |:.   .....|.:....:.| .|....|:.::......|.. |...||  |:....:.:...:.
Mouse   376 LQW---NHVSSCILNGGGIRG-PIDERNRNGSITMEDLIAVLPFGGTFDLVQLNGSTLLEAFEHS 436

  Fly   418 VGSHCGVSIGEDGPSQMGLEDIAMFRAIPGSTVFYPADAV--STERAVEMAANTPGVCFIRTSRP 480
            |..| |.:.||             |..:.|..|.|.....  |..::|::......|.......|
Mouse   437 VRRH-GGNTGE-------------FLQVSGFQVVYDLSKAPGSRVKSVKVLCTQCRVPHYEPLVP 487

  Fly   481 N-------TAVIYENNEKFEIGKCKVVKQNANDSVLLIGAGITLYEALKAAEELEKSGIHCRVID 538
            |       .:.:.:..:.|.:.|.|.:|.::.|..:.:.||..          .|:..:|..|
Mouse   488 NKVYKVVLPSYLVDGGDGFTMIKEKKLKHDSGDLDISVVAGYI----------SERKRVHPAV-- 540

  Fly   539 PFTVKPLDQEGIIKHGAQCGG 559
                     ||..:..:.|.|
Mouse   541 ---------EGRFQFSSSCAG 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4271	NP_608665.1	Tryp_SPc	19..234	CDD:238113	36/179 (20%)
Klk1b8	NP_032483.1	Tryp_SPc	24..253	CDD:214473	39/185 (21%)