Protein Alignment Sec24CD and CEF

DIOPT Version :9

• Sequence 1: NP_001259918.1
• Gene: Sec24CD / 33409
• FlyBaseID: FBgn0262126
• Length: 1231
• Species: Drosophila melanogaster
• Sequence 2: NP_001326943.1
• Gene: CEF / 823559
• AraportID: AT3G44340
• Length: 1096
• Species: Arabidopsis thaliana
• Alignment Length: 1186
• Identity: 411/1186 - (34%)
• Similarity: 592/1186 - (49%)
• Gaps: 193/1186 - (16%)

  Fly   110 AAPPPTGFNQFNSNAAPPPTNNNNAAFGAPPPTQAGSYVNGALPPSSTPQSVASGINQMSLNSAT 174
            |||.|.|       |..|  |||....|.||....||..|        |.|:|:.:..:::|
plant     2 AAPVPPG-------AYRP--NNNQQNSGGPPNFVPGSQGN--------PNSLAANMQNLNIN--- 46

  Fly   175 LAGLPHMPPPKAATPGAAPGQPPIPAAGSTSQPPLPGQPPLPGQPPFSGQIPTS-------QPAP 232
                                :||         ||:||..|.| .||| ||.|.|       ||.|
plant    47 --------------------RPP---------PPMPGSGPRP-SPPF-GQSPQSFPQQQQQQPRP 80

  Fly   233 SPYGVPSSRPGQPQLPPGAT-----PPTYTQP-GLPPQQQQGIPPLQQP---GIPQQQP------ 282
            |    |.:|||.|  ||.|.     ||..:|| |.||..:...||..||   |.|...|
plant    81 S----PMARPGPP--PPAAMARPGGPPQVSQPGGFPPVGRPVAPPSNQPPFGGRPSTGPLVGGGS 139

  Fly   283 ------GFPPQQP-----------------GLPPLSQPG--LPPQPGAPYG----APQQGGYSGG 318
                  |||...|                 |.||...||  :||..|.|.|    .|...|..||
plant   140 SFPQPGGFPASGPPGGVPSGPPSGARPIGFGSPPPMGPGMSMPPPSGMPGGPLSNGPPPSGMHGG 204

  Fly   319 F--PGQAPGGFPGAP----PPLP---------GQQAAAPPQFGAPQPGYPGQQPGYPPQPGQQPM 368
            .  .|..|.|.||.|    ||.|         |.|..:.|.. ||.|.| ||.|...|..|..|:
plant   205 HLSNGPPPSGMPGGPLSNGPPPPMMGPGAFPRGSQFTSGPMM-APPPPY-GQPPNAGPFTGNSPL 267

  Fly   369 PGYP----PQPGQQLGGP-GYPPQPGAGFPGQPGRPGFNQPPMPGA-GNMYQQAPQAR------- 420
            ...|    |.|....|.| |.||.|| |||  .|.|....|..||. |::|...|...
plant   268 SSPPAHSIPPPTNFPGVPYGRPPMPG-GFP--YGAPPQQLPSAPGTPGSIYGMGPMQNQSMTSVS 329

  Fly   421 ---RLDPDQMPNP--------IQVMIENQRLSGGPFVTNQPGLLPPLVTTKFVVHDQGNSSPRFL 474
               ::|.:|:|.|        .:..:||:   ..|         ||..|..::..|.||||||::
plant   330 SPSKIDLNQIPRPGSSSSPIVYETRVENK---ANP---------PPPTTVDYITRDTGNSSPRYM 382

  Fly   475 RSSLYCIPNTGDLLKTTALPLTLNISPLAKVGEGEMEPPIVNFGEMGPIRCNRCKAYMSPNMQFV 539
            |.::..||.|.|||.|:.:.|.|.:.|:|.....|....:|:|||.||:||:|||.|::|.|:|:
plant   383 RCTINQIPCTVDLLSTSGMQLALIVQPMALSHPSEEPIQVVDFGESGPVRCSRCKGYVNPFMKFI 447

  Fly   540 DAGRRFQCLMCKVTSEVHQNYYQHLDHTGQRVDKHERPELLLGTYEFLATKDYCRNNTPPEVPAF 604
            |.||:|.|.:|..|.|..::|..:|...|:|.|..|||||..||.:|:|||:|...:..|.|  :
plant   448 DQGRKFICNLCGYTDETPRDYQCNLGPDGRRRDADERPELCRGTVDFVATKEYMVRDPMPAV--Y 510

  Fly   605 IFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDQGQDKSKVRVGFITYNSTVHFYNIKSSLAQPQ 669
            .|:||||.|.:::|.....||.|:.:|..||     :..:..||..|::||:||||:|.:|.||.
plant   511 FFLIDVSMNAIQTGATAAACSAIQQVLSDLP-----EGPRTFVGIATFDSTIHFYNLKRALQQPL 570

  Fly   670 MMVVGDVQEMFMPLLDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALKASN 734
            |::|.|||:::.||....:....|....::.|:|.||.||.::|..|:....|::|...|:|::
plant   571 MLIVPDVQDVYTPLETDVIVQLSECRQHLEILLESIPTMFQESKSPESAFGAAVKAAFLAMKST- 634

  Fly   735 AAGKLLVFNSTLPIAEAPGKLKNRD-DRKLLGTDKEK---TVLTPQTTAYNTLGQECVQQGCSVD 795
             .|||:||.|.|| :...|.|.:|: |.:...:..||   .:|.|......|:..|..:....||
plant   635 -GGKLMVFQSVLP-SVGIGALSSREADGRANASAGEKEAHKLLQPADKTLRTMAIEFAEYQVCVD 697

  Fly   796 LFVFNNAYIDLATIGQVSRLTGGEVFKYTYFQADVDGKRLIQDIIKNVSRPIAFDAVMRVRTSAG 860
            ||:...||:|:|:|.::.|.|||:|:.|..|.|..|..:|..|:..|::||..|:||||||.|.|
plant   698 LFITTQAYVDMASISEIPRTTGGQVYCYYPFSALSDPPKLYNDLRWNITRPQGFEAVMRVRCSQG 762

  Fly   861 IRPTEFYGHFFMSNTTDVELASIDATKSISIEIKHDDKLAPEENVYLQVALLYTSCSGQRRLRIL 925
            |:..|:.|:|.....||::|.:||..|:|.:.:||||||........|.|||||:.||:||:|:|
plant   763 IQVQEYSGNFCKRIPTDIDLPAIDCDKAIMVTLKHDDKLQDGAECGFQCALLYTTISGERRIRVL 827

  Fly   926 NLALRVTTTIADVFKCCDLDAMMLFFAKQACFKLMEHSPKQVKDNLIHRSAQILACYRKHCTSPT 990
            ||::..|..::::|:..|||:......|||..::...:...||:...:....||..|||.|.:.|
plant   828 NLSIPCTNMLSNLFRSADLDSQFACMLKQAANEIPSKALPLVKEQATNDCITILHSYRKFCATVT 892

  Fly   991 SAGQLILPECLKLLPLYASCLLKNDAISGGSDMTLDDRSYVIQFILSMDLNQSVSYLYPRFIPIH 1055
            |.|||||||.|||||||...|.|...:.  .|..:||||:.|..:.|:....::..:|||.|.:|
plant   893 STGQLILPEALKLLPLYTLALTKGVGLR--MDGRIDDRSFWINHVSSLSTPLAIPLVYPRMIAVH 955

  Fly  1056 NVVP---EETDLPTPVRCTHEKTQEDGAYILENGVHLFVWLGQALSPDFVQSVFGVQGL----QQ 1113
            ::..   ||..:|.|:....|...::|.|.||||....:::|::::.|.:|.:|.|:..    .|
plant   956 DLDANDNEENVVPCPIPLQSEHLSDEGVYFLENGEDGLIYIGESVNSDILQKLFNVRSAAELPSQ 1020

  Fly  1114 IALERFNIVPETPLAKRIHGILEQIMKERSRYMRITWLRQNDKL-ESVFRHFLVEDRGTDGSASY 1177
            ..|:::    :..|:|:.:.::.:|.::||.|:||...::.|.. ..:|:.::|||||: |.|||
plant  1021 YVLQKY----DNQLSKKFNDVVNEIRRQRSSYLRIKLCKKGDPAGNMLFQSYMVEDRGS-GGASY 1080

  Fly  1178 VDFLCHMHKEIKDLLS 1193
            ||||..:|::|:..|:
plant  1081 VDFLVSVHRQIQHKLN 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec24CD	NP_001259918.1	COG5028	395..1190	CDD:227361	296/825 (36%)
		zf-Sec23_Sec24	522..559	CDD:282641	18/36 (50%)
		Sec24-like	599..847	CDD:238756	88/251 (35%)
		Sec23_BS	848..932	CDD:285301	40/83 (48%)
		Sec23_helical	950..1043	CDD:282646	36/92 (39%)
		Gelsolin	1061..1135	CDD:279020	19/77 (25%)
CEF	NP_001326943.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	142	1.000	Domainoid score	I1514
eggNOG	1	0.900	-	-		E1_COG5028
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	586	1.000	Inparanoid score	I233
OMA	1	1.010	-	-		QHG53542
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001889
OrthoInspector	1	1.000	-	-		otm3294
orthoMCL	1	0.900	-	-		OOG6_101536
Panther	1	1.100	-	-	O	PTHR13803
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1423
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830