Protein Alignment Sec24CD and Sec24CD

DIOPT Version :10

• Sequence 1: NP_001259918.1
• Gene: Sec24CD / 33409
• FlyBaseID: FBgn0262126
• Length: 1231
• Species: Drosophila melanogaster
• Sequence 2: XP_314929.4
• Gene: Sec24CD / 1275660
• VectorBaseID: AGAMI1_013948
• Length: 1113
• Species: Anopheles gambiae
• Alignment Length: 1241
• Identity: 693/1241 - (55%)
• Similarity: 828/1241 - (66%)
• Gaps: 176/1241 - (14%)

  Fly     1 MNPNMYGPPPTQFQQQPQFGAPPPNSGGWP-PQQQQLPQQQPPQQQLPPQQQQQQPQYGAPPPTS 64
            |||            |..:|..||.|  || ||||..||..||    ||          .|.|:.
Mosquito     1 MNP------------QLAYGQYPPQS--WPQPQQQVAPQAGPP----PP----------GPKPSM 37

  Fly    65 AASQPYLNGNYQQQLATSMGGLSVGGGVGGANPLKPPLPQGAPAAAAPPPTGFNQFNSNAAPPPT 129
            ..:||      .||||..|..:|:.|     .|.:..||||.|....||
Mosquito    38 NGAQP------NQQLANQMQNMSLAG-----QPPQQQLPQGPPKMGGPP---------------- 75

  Fly   130 NNNNAAFGAPP---PTQ---------AGSYVNGALPPSSTPQSVASGINQMSLNSATLAGLPHMP 182
            |.|....||||   |||         .|..:.||.||:...|      .|.......::..|..|
Mosquito    76 NMNGPGVGAPPAAFPTQQPPMVRPPSTGGPMPGAYPPAPQQQ------QQQQPGPGMMSNGPSGP 134

  Fly   183 PPKAATPGAAPGQPPIPAAGSTSQPPLPGQPPLPGQPPFSGQIPTSQPAPSPYGVPSSRPGQPQL 247
            |    .|||.  :||:|.||...|        ..|.|         ..||.|.|....:.|.|.
Mosquito   135 P----GPGAV--RPPMPTAGGYGQ--------TNGHP---------MAAPPPAGPTGQQFGGPM- 175

  Fly   248 PPGATPPTYTQP-GLPPQQQQGIPPLQQPGIPQQQP--GFPPQQPGLPPLSQPGLPPQPGAPYGA 309
                  |:.|.| |.||:..|..||  ||...||||  |||| ..|.||.:|       |.||||
Mosquito   176 ------PSMTAPGGGPPRPGQQFPP--QPAAFQQQPPAGFPP-GGGAPPQTQ-------GMPYGA 224

  Fly   310 PQQGGYSGGFPGQAPGGFPGAPPPLPGQQAAAPPQFGAPQPGYPGQQP-GYPPQPGQQPMPGYPP 373
            |.    .|..|.|....:||  ||:|||....|.|    ||    ||| ||||||||.     ||
Mosquito   225 PP----GGPAPAQPQQQYPG--PPMPGQPMQPPQQ----QP----QQPQGYPPQPGQM-----PP 270

  Fly   374 QPGQQLGGPGYPPQ------PGAGF---PGQPGRPGFNQPPMPGAGNMYQQ-------------- 415
            ..||.      ||:      ||||:   |..||:|. .||.......|:||
Mosquito   271 MGGQM------PPRGYNQMPPGAGYNQMPPMPGQPP-QQPQQTQQQQMHQQPPYHQGGPGMMGGH 328

  Fly   416 ------APQARRLDPDQMPNPIQVMIENQRLSGGPFVTNQPGLLPPLVTTKFVVHDQGNSSPRFL 474
                  .||.:||||:.||||||||.|||...||.|.|||||.||||||||||..||||:||||:
Mosquito   329 YPAPPPVPQQKRLDPESMPNPIQVMAENQENCGGVFCTNQPGQLPPLVTTKFVTQDQGNASPRFV 393

  Fly   475 RSSLYCIPNTGDLLKTTALPLTLNISPLAKVGEGEMEPPIVNFGEMGPIRCNRCKAYMSPNMQFV 539
            ||::|.||.|.|::|.:|:|.:|.|||.|:..|||:..|||||||||||||.|||||:.|.|||:
Mosquito   394 RSTMYNIPQTADMMKQSAVPFSLIISPFARTVEGELPIPIVNFGEMGPIRCIRCKAYICPTMQFL 458

  Fly   540 DAGRRFQCLMCKVTSEVHQNYYQHLDHTGQRVDKHERPELLLGTYEFLATKDYCRNNTPPEVPAF 604
            |.||||||..||.|::|.|.|:|||||||||:||:|||||:||||||:|||:||||||||:.||.
Mosquito   459 DGGRRFQCQFCKATTDVPQGYFQHLDHTGQRMDKYERPELVLGTYEFMATKEYCRNNTPPKPPAM 523

  Fly   605 IFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDQGQDKSKVRVGFITYNSTVHFYNIKSSLAQPQ 669
            :|:||||||.||||||.|||||::||::.|||||.|.::.::||||||||:|||||:||||||||
Mosquito   524 VFLIDVSYNNVKSGLVQLLCSQMRNIIRQLPVDQDQQRTSMKVGFITYNSSVHFYNLKSSLAQPQ 588

  Fly   670 MMVVGDVQEMFMPLLDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALKASN 734
            ||||||:||||||||||||...||||.|||||||:||:||.||:||||||.||:||||||||||.
Mosquito   589 MMVVGDLQEMFMPLLDGFLVDAEESATVIDALMEQIPKMFGDTRETETILLPALQAGLEALKASE 653

  Fly   735 AAGKLLVFNSTLPIAEAPGKLKNRDDRKLLGTDKEKTVLTPQTTAYNTLGQECVQQGCSVDLFVF 799
            ..|||.||:|:||.||||||||.||||||||||||||||:||:|.||.|.|:||..|.|||||.|
Mosquito   654 CVGKLYVFHSSLPNAEAPGKLKIRDDRKLLGTDKEKTVLSPQSTVYNMLAQDCVGAGVSVDLFAF 718

  Fly   800 NNAYIDLATIGQVSRLTGGEVFKYTYFQADVDGKRLIQDIIKNVSRPIAFDAVMRVRTSAGIRPT 864
            |||||||||||||:|||||||:||||||||:||.||:.|::||:|||||||||||||||.|:|||
Mosquito   719 NNAYIDLATIGQVARLTGGEVYKYTYFQADIDGARLVNDLMKNISRPIAFDAVMRVRTSTGVRPT 783

  Fly   865 EFYGHFFMSNTTDVELASIDATKSISIEIKHDDKLAPEENVYLQVALLYTSCSGQRRLRILNLAL 929
            :||||||||||.|:|:||||..||:|:||||||||. :|.|.:||||||||||||||||:.||:|
Mosquito   784 DFYGHFFMSNTKDMEIASIDCDKSVSVEIKHDDKLT-DELVLIQVALLYTSCSGQRRLRVHNLSL 847

  Fly   930 RVTTTIADVFKCCDLDAMMLFFAKQACFKLMEHSPKQVKDNLIHRSAQILACYRKHCTSPTSAGQ 994
            ::.|::.|:|:|||||..:|:||||...|||:::||.|||.::||:.|:||||||||.||||:||
Mosquito   848 KMCTSLLDLFRCCDLDTTLLYFAKQGLTKLMDNNPKAVKDAIVHRAVQLLACYRKHCASPTSSGQ 912

  Fly   995 LILPECLKLLPLYASCLLKNDAISGGSDMTLDDRSYVIQFILSMDLNQSVSYLYPRFIPIHNVVP 1059
            |||||.:||||||.:|||||||.|||||:::|||||||.:::||||..||.|.|||.||:|:|..
Mosquito   913 LILPEGMKLLPLYVNCLLKNDAFSGGSDISIDDRSYVIYYVMSMDLPTSVQYFYPRLIPLHDVNV 977

  Fly  1060 EETDLPTPVRCTHEKTQEDGAYILENGVHLFVWLGQALSPDFVQSVFGVQGLQQIALERFNI-VP 1123
            |...:|..:|||.:|..||||||||||||:|:|||.:|||:|.|||||.|..||:..:|..: |.
Mosquito   978 EGDAIPAAIRCTGDKMHEDGAYILENGVHMFLWLGLSLSPEFTQSVFGAQCTQQVDTDRTGLPVF 1042

  Fly  1124 ETPLAKRIHGILEQIMKERSRYMRITWLRQNDKLESVFRHFLVEDRG-TDGSASYVDFLCHMHKE 1187
            :.||:|||.||:::|.:::.|.||:|.::|.||||||.||||||||| ||||.||||||||:|||
Mosquito  1043 DNPLSKRIRGIVDKIQEQKRRCMRLTLVKQRDKLESVLRHFLVEDRGTTDGSVSYVDFLCHVHKE 1107

  Fly  1188 IKDLLS 1193
            |:.:||
Mosquito  1108 IRQMLS 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec24CD	NP_001259918.1	PRK12323	<119..321	CDD:481241	66/216 (31%)
		COG5028	395..1190	CDD:227361	551/816 (68%)
Sec24CD	XP_314929.4	None