DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4270 and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_608663.1	Gene:	CG4270 / 33408	FlyBaseID:	FBgn0031407	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	168	Identity:	37/168 - (22%)
Similarity:	65/168 - (38%)	Gaps:	38/168 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RGQDTKGNNELFLKEVFNTTNKYRAM-----HGCPAVTINAALNKLAQEWANHLRDQNTMAHRPN 79
            ||:....:|:  ::.:.:..||.|:.     .....:|.:..|.:.|:.||    :.....|.|.
Human    52 RGKRAITDND--MQSILDLHNKLRSQVYPTASNMEYMTWDVELERSAESWA----ESCLWEHGPA 110

  Fly    80 ---PKYGENIFLSGGMDVTGDLPVEMWYREINSYDFNKAQFV----------PTAGHFTQLIWKS 131
               |..|:|:....|........|:.||.|:..:.:......          |...|:||::|.:
Human   111 SLLPSIGQNLGAHWGRYRPPTFHVQSWYDEVKDFSYPYEHECNPYCPFRCSGPVCTHYTQVVWAT 175

  Fly   132 SVEMGSGVA------------RKADRTWVVCNYNPPGN 157
            |..:|..:.            .||  .::||||:|.||
Human   176 SNRIGCAINLCHNMNIWGQIWPKA--VYLVCNYSPKGN 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4270	NP_608663.1	SCP_GAPR-1_like	31..158	CDD:240182	34/157 (22%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180	30/149 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281
		LCCL	291..375	CDD:128866
		LCCL	392..483	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2242
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850