DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4270 and Crispld2

DIOPT Version :9

Sequence 1:	NP_608663.1	Gene:	CG4270 / 33408	FlyBaseID:	FBgn0031407	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	NP_001297564.1	Gene:	Crispld2 / 78892	MGIID:	1926142	Length:	495	Species:	Mus musculus

Alignment Length:	156	Identity:	39/156 - (25%)
Similarity:	64/156 - (41%)	Gaps:	32/156 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KEVFNTTNKYRAMHGCPA-----VTINAALNKLAQEWANHLRDQNTMAHRPN---PKYGENIFLS 89
            :|:....||.|.....||     :|.:..|.:.|..||:..    ...|.|.   ...|:|:.:.
Mouse    57 QEILMLHNKLRGQVYPPASNMEHMTWDEELERSAAAWAHRC----LWEHGPAGLLRSIGQNLAVH 117

  Fly    90 GGMDVTGDLPVEMWYREINSYDF----------NKAQFVPTAGHFTQLIWKSSVEMGSGV--ARK 142
            .|...:....|:.||.|:..|.:          .:....|...|:||::|.::.::|..|  .|.
Mouse   118 WGRYRSPGFHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRN 182

  Fly   143 AD---RTW-----VVCNYNPPGNVVG 160
            .:   .||     :||||:|.||.:|
Mouse   183 MNVWGDTWENAVYLVCNYSPKGNWIG 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4270	NP_608663.1	SCP_GAPR-1_like	31..158	CDD:240182	37/152 (24%)
Crispld2	NP_001297564.1	CAP	56..201	CDD:381818	34/147 (23%)
		LCCL	284..368	CDD:128866
		LCCL	387..486	CDD:367672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2242
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850