DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4270 and CRISP2

DIOPT Version :9

Sequence 1:	NP_608663.1	Gene:	CG4270 / 33408	FlyBaseID:	FBgn0031407	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	XP_005249406.1	Gene:	CRISP2 / 7180	HGNCID:	12024	Length:	278	Species:	Homo sapiens

Alignment Length:	142	Identity:	41/142 - (28%)
Similarity:	66/142 - (46%)	Gaps:	28/142 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KEVFNTTNKYRAMHGCPA-----------VTINAALNKLAQEWANH--LRDQNTMAHRPNPKYGE 84
            :|:.|..|:.|.....||           ||.|      ||.|||.  |:..:....:.:.:.||
Human    38 REIVNKHNELRKAVSPPASNMLKMEWSREVTTN------AQRWANKCTLQHSDPEDRKTSTRCGE 96

  Fly    85 NIFLSGGMDVTG-DLPVEMWYREINSYDFNKAQFVPTA--GHFTQLIWKSSVEMGSGVA----RK 142
            |:::|.  |.|. ...::.||.||..:.:......|.|  ||:|||:|.|:.::|.|:|    :.
Human    97 NLYMSS--DPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPNQD 159

  Fly   143 ADRTWVVCNYNP 154
            :.:.:.||.|.|
Human   160 SLKYYYVCQYCP 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4270	NP_608663.1	SCP_GAPR-1_like	31..158	CDD:240182	41/142 (29%)
CRISP2	XP_005249406.1	SCP_CRISP	35..172	CDD:240183	41/142 (29%)
CRISP2	XP_005249406.1	Crisp	224..278	CDD:285731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920