DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4270 and PI16

DIOPT Version :9

Sequence 1:	NP_608663.1	Gene:	CG4270 / 33408	FlyBaseID:	FBgn0031407	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	175	Identity:	49/175 - (28%)
Similarity:	70/175 - (40%)	Gaps:	34/175 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GPRGQDTKGNNELFLKEVFNTTNKYRAMHGCPAVTINAALNKLAQEWANHL-------RDQNTMA 75
            ||.|..|.....|.::    ..|.|||.      ....|.:.|...|...|       ..|....
Human    23 GPVGALTDEEKRLMVE----LHNLYRAQ------VSPTASDMLHMRWDEELAAFAKAYARQCVWG 77

  Fly    76 H-RPNPKYGENIF--LSGGMDVTGDLPVEMWYREINSYDFNKAQFVP--TAGHFTQLIWKSSVEM 135
            | :...:.|||:|  ...||||  .|.:|.|:.|...|:.:.|...|  ..||:||::|..:..:
Human    78 HNKERGRRGENLFAITDEGMDV--PLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERI 140

  Fly   136 GSGV--------ARKADRTWVVCNYNPPGNVVGL--FKDNVPPKQ 170
            |.|.        ..:.:...:||||.|||||.|.  :::..|..|
Human   141 GCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQ 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4270	NP_608663.1	SCP_GAPR-1_like	31..158	CDD:240182	39/146 (27%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	36/144 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820