DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4270 and GLIPR2

DIOPT Version :9

Sequence 1:	NP_608663.1	Gene:	CG4270 / 33408	FlyBaseID:	FBgn0031407	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	NP_001273942.1	Gene:	GLIPR2 / 152007	HGNCID:	18007	Length:	169	Species:	Homo sapiens

Alignment Length:	153	Identity:	56/153 - (36%)
Similarity:	84/153 - (54%)	Gaps:	8/153 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KGNNELFLKEVFNTTNKYRAMHGCPAVTINAALNKLAQEWANHLRDQNTMAHRPNP---KYGENI 86
            |..::.|..||....|:||..||.|.:.:...||:.||:::..|.....:.|.|..   :.|||:
Human    18 KPASKQFHNEVLKAHNEYRQKHGVPPLKLCKNLNREAQQYSEALASTRILKHSPESSRGQCGENL 82

  Fly    87 FLSGGMDVTGDLPVEMWYREINSYDFNKAQFVPTAGHFTQLIWKSSVEMGSGVARKAD-RTWVVC 150
            ..: ..|.||....:.||.||.:|:|.:..|....||||.::||::.:||.|.|..:| .::||.
Human    83 AWA-SYDQTGKEVADRWYSEIKNYNFQQPGFTSGTGHFTAMVWKNTKKMGVGKASASDGSSFVVA 146

  Fly   151 NYNPPGNVV--GLFKDNV-PPKQ 170
            .|.|.||||  |.|::|| |||:
Human   147 RYFPAGNVVNEGFFEENVLPPKK 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4270	NP_608663.1	SCP_GAPR-1_like	31..158	CDD:240182	45/130 (35%)
GLIPR2	NP_001273942.1	SCP_GAPR-1_like	23..154	CDD:240182	45/131 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49417
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	1	1.000	-	-		FOG0001021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101367
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2242
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.820