DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4270 and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_608663.1	Gene:	CG4270 / 33408	FlyBaseID:	FBgn0031407	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	160	Identity:	37/160 - (23%)
Similarity:	64/160 - (40%)	Gaps:	32/160 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 FLKEVFNTTNKYRA-----MHGCPAVTINAALNKLAQEWAN--------HLRDQNTMAHRPNPKY 82
            |:.|..|..|:.|.     ......:|.:.||::.|:.|..        :|:|.. |.|   ||:
Human    53 FINEYVNLHNELRGDVIPRGSNLRFMTWDVALSRTARAWGKKCLFTHNIYLQDVQ-MVH---PKF 113

  Fly    83 ---GENIFLSGGMDVTGDLPVEMWYREINSYDFNKAQFVPTAGHFTQLIWKSSVEMG------SG 138
               |||:::....:.|..:.:..|:.|...|:|..........::.||:|..|.::|      |.
Human   114 YGIGENMWVGPENEFTASIAIRSWHAEKKMYNFENGSCSGDCSNYIQLVWDHSYKVGCAVTPCSK 178

  Fly   139 VARKADRTWVVCNYNPPGNVV------GLF 162
            :.........:|||.|.|.:.      |:|
Human   179 IGHIIHAAIFICNYAPGGTLTRRPYEPGIF 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4270	NP_608663.1	SCP_GAPR-1_like	31..158	CDD:240182	35/148 (24%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	33/145 (23%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151125
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750