Protein Alignment Send1 and TPSB2

DIOPT Version :10

• Sequence 1: NP_608662.1
• Gene: Send1 / 33407
• FlyBaseID: FBgn0031406
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 85/278 - (30%)
• Similarity: 120/278 - (43%)
• Gaps: 61/278 - (21%)

  Fly     8 LLLAVHLLISP--VVPVLLEPSER--IIGGSSMDITDVPWQVSLQY---YGEHFCGGSIYSKTII 65
            ||||:.:|.|.  ..|...:..:|  |:||.....:..||||||:.   |..||||||:.....:
Human     5 LLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWV 69

  Fly    66 ITAAHCIKEGERSIRAGSSLHDSGGV--------------VVGVEAYIIHPQFDKHNMENDVAVL 116
            :|||||:         |..:.|...:              ::.|...|:||||....:..|:|:|
Human    70 LTAAHCV---------GPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALL 125

  Fly   117 KLSSPLSFSDSIQTI---PLAETDPPTSSSALATGWG---RGNFLIRPRQLQGVEILIRPLIVCK 175
            :|..|::.|..:.|:   |.:||.|| ......||||   ....|..|..|:.|::.|....:|.
Human   126 ELEEPVNVSSHVHTVTLPPASETFPP-GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICD 189

  Fly   176 LKYGNGVFNED---------ICAGRMGKGGCYGDSGGPLV--FNGQLVGITSRTGNIVCLGS--- 226
            .||..|.:..|         :|||...:..|.||||||||  .||     |.....:|..|.
Human   190 AKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNG-----TWLQAGVVSWGEGCA 249

  Fly   227 -----SLYASVARYRNWI 239
                 .:|..|..|.:||
Human   250 QPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	76/253 (30%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	77/252 (31%)