DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Send1 and PRSS2

DIOPT Version :9

Sequence 1:NP_608662.1 Gene:Send1 / 33407 FlyBaseID:FBgn0031406 Length:255 Species:Drosophila melanogaster
Sequence 2:NP_001290343.1 Gene:PRSS2 / 5645 HGNCID:9483 Length:261 Species:Homo sapiens


Alignment Length:269 Identity:82/269 - (30%)
Similarity:124/269 - (46%) Gaps:48/269 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 LLAVHLLISPVVPVLLEPSERIIGGSSMDITDVPWQVSLQYYGEHFCGGSIYSKTIIITAAHCIK 73
            ||.:...::..|....:..::|:||...:...||:||||. .|.||||||:.|:..:::|.||.|
Human     3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLN-SGYHFCGGSLISEQWVVSAGHCYK 66

  Fly    74 EGERS-------------IRAGSSLHDSGGVVVGVEAY------IIHPQFDKHNMENDVAVLKLS 119
            ....|             :|.|.  |:. .|:.|.|.:      |.||:::...::||:.::|||
Human    67 SAINSKLSGRGCEYHRIQVRLGE--HNI-EVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLS 128

  Fly   120 SPLSFSDSIQTIPLAETDPPTSSSALATGWGRGNFLIR----PRQLQGVEILIRPLIVCKLKYGN 180
            ||...:..:..|.|....|...:.:|.:||  ||.|..    |.:||.::..:.....|:..|..
Human   129 SPAVINSRVSAISLPTAPPAAGTESLISGW--GNTLSSGADYPDELQCLDAPVLSQAECEASYPG 191

  Fly   181 GVFNEDICAGRM--GKGGCYGDSGGPLVFNGQLVGITS---------RTGNIVCLGSSLYASVAR 234
            .:.|...|.|.:  ||..|.||||||:|.||:|.||.|         |.|        :|..|..
Human   192 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPG--------VYTKVYN 248

  Fly   235 YRNWILSAI 243
            |.:||...|
Human   249 YVDWIKDTI 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Send1NP_608662.1 Tryp_SPc 29..239 CDD:214473 76/243 (31%)
Tryp_SPc 30..239 CDD:238113 76/242 (31%)
PRSS2NP_001290343.1 Tryp_SPc 23..253 CDD:214473 76/243 (31%)
Tryp_SPc 24..256 CDD:238113 78/245 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.