DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Send1 and Prss53

DIOPT Version :9

Sequence 1:	NP_608662.1	Gene:	Send1 / 33407	FlyBaseID:	FBgn0031406	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	78/312 - (25%)
Similarity:	127/312 - (40%)	Gaps:	89/312 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLISPVVPVL--LEPSERIIG-----------GSSMDITDVPWQVSLQYYGEHFCGGSIYSKTII 65
            |||...|.|:  |:.::|..|           |:::. .:.|||.|::..|.|.|.||:.:.|.:
  Rat     9 LLIVGAVIVIEGLQAAQRACGQRGPGPPEPQEGNTLP-GEWPWQASVRRQGVHICSGSLVADTWV 72

  Fly    66 ITAAHCIKE------GERSIRAGSSLHDS---GGVVVGVEAYIIHPQFDKHNMENDVAVLKLSSP 121
            :|||||.::      ...|:..||...:.   |...|||.|..:...::.::..:|:|:|:|:.|
  Rat    73 LTAAHCFEKMATAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHP 137

  Fly   122 LSFSDSIQT---IPLAETDPPTSSSALATGWGR----GNFLIR--PRQLQGVEIL---------- 167
            :     :.|   :|......|..:|..||||.:    |.:..|  .|:.|...:|
  Rat   138 I-----VHTTLCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQTGSVLTVLALCSHCV 197

  Fly   168 ------IRPLIV----------------CKLKY--------GNGVFNEDICAGRMG--KGGCYGD 200
                  :.||.|                |...|        .|...:..:|.|...  :|.|.||
  Rat   198 SELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQRLLANPARSGMLCGGAQPGVQGPCQGD 262

  Fly   201 SGGPLVF---NGQ--LVGITSRTGNIVCLGSS---LYASVARYRNWILSAID 244
            ||||::.   :|.  .|||.|.|.|  |....   |...:|.:.:|:.:.:|
  Rat   263 SGGPVMCREPDGHWVQVGIISFTSN--CAQEDTPVLLTDMAAHSSWLQAHVD 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	70/288 (24%)
Send1	NP_608662.1	Tryp_SPc	30..239	CDD:238113	69/287 (24%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	68/272 (25%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343311
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030