DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Send1 and Prss36

DIOPT Version :9

Sequence 1:	NP_608662.1	Gene:	Send1 / 33407	FlyBaseID:	FBgn0031406	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	89/296 - (30%)
Similarity:	127/296 - (42%)	Gaps:	80/296 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LAVHLLISPVVPV----------------------LLEPSERIIGGSSMDITDVPWQVSLQYYGE 52
            |..||:.|.|.|.                      ..|||.||:|||.......||||||.:.|.
  Rat    17 LTPHLVFSVVSPTPGAFQDSAVSPTQGEFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVSLHHGGG 81

  Fly    53 HFCGGSIYSKTIIITAAHC-IKEG------ERSIRAGSSLHDSGGVVVG-----VEAYIIHPQFD 105
            |.||||:.:.:.:::|||| :..|      |.|:..|  :|...|.:.|     |...::...:.
  Rat    82 HICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLLG--VHSQDGPLEGAHMRSVATILVPDNYS 144

  Fly   106 KHNMENDVAVLKLSSPLSFSDSIQTIPLAETDPPTS------SSALATGWG---RGNFLIRPRQL 161
            :..:..|:|:|:|:||.....|::.:.|    |..|      ::..|||||   ..:.|..|..|
  Rat   145 RVELGADLALLRLASPAKLGPSVKPVCL----PRASHLFAHGTACWATGWGDVQESDPLPVPWVL 205

  Fly   162 QGVEILIRPLIVCKLKYGN-GVFNED-------ICAG--RMGKGGCYGDSGGPLVF--NGQ--LV 212
            |.||:.:.....|:..|.. |.||..       :|||  ...:..|.||||||||.  .|:  |.
  Rat   206 QEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLCAGYPEGRRDTCQGDSGGPLVCEDGGRWFLA 270

  Fly   213 GITS---------RTGNIVCLGSSLYASVARYRNWI 239
            ||||         |.|        ::.:||.|.:||
  Rat   271 GITSFGFGCGRRNRPG--------VFTAVAHYESWI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	78/253 (31%)
Send1	NP_608662.1	Tryp_SPc	30..239	CDD:238113	77/252 (31%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	79/254 (31%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030