DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Send1 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_608662.1	Gene:	Send1 / 33407	FlyBaseID:	FBgn0031406	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	239	Identity:	75/239 - (31%)
Similarity:	113/239 - (47%)	Gaps:	36/239 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RIIGGSSMDITDVPWQVSLQYYGEHFCGGSIYSKTIIITAAHCIKEGERSIRAGS--SLHDSGGV 91
            ::.||...:..:.|||.|||....|.||.::.|.:.:||||||.      :|:.:  ....|.|.
  Rat   186 KVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCF------VRSANPKDWKVSFGF 244

  Fly    92 VV-------GVEAYIIHPQFDKHNMENDVAVLKLSSPLSFSDSIQ--TIPLAETDPPTSSSALAT 147
            ::       .|::.:||..:......||:||::||||:.:.::|:  .:|.|....|.:|..:.|
  Rat   245 LLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVT 309

  Fly   148 GWGR----GNFLIRPRQLQGVEILIRPLIVCK--LKYGNGVFNEDICAGRM-GK-GGCYGDSGGP 204
            |||.    |:   .|..||...:.|.....|.  ..||..:....:|||.: |: ..|.||||||
  Rat   310 GWGTLKSDGD---SPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGP 371

  Fly   205 LVFNGQ-----LVGITSRTGNIVCLGS--SLYASVARYRNWILS 241
            ||....     |.||.| .|:...|.:  .:|..|..||:||.|
  Rat   372 LVSEDSKGIWFLAGIVS-WGDECALPNKPGVYTRVTHYRDWISS 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	72/235 (31%)
Send1	NP_608662.1	Tryp_SPc	30..239	CDD:238113	72/234 (31%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	72/235 (31%)
		Tryp_SPc	187..415	CDD:238113	75/238 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920