Protein Alignment Send1 and HPN

DIOPT Version :10

• Sequence 1: NP_608662.1
• Gene: Send1 / 33407
• FlyBaseID: FBgn0031406
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 94/265 - (35%)
• Similarity: 127/265 - (47%)
• Gaps: 53/265 - (20%)

  Fly    26 PSERIIGGSSMDITDVPWQVSLQYYGEHFCGGSIYSKTIIITAAHCIKEGERSIR---------A 81
            |.:||:||....:...||||||:|.|.|.||||:.|...::|||||..|..|.:.         |
Human   159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVA 223

  Fly    82 GSSLHDSGGVVVGVEAYIIH----PQFDKHNME--NDVAVLKLSSPLSFSDSIQTIPLAETDPPT 140
            .:|.|   |:.:||:|.:.|    |..|.::.|  ||:|::.|||||..::.||.:.|     |.
Human   224 QASPH---GLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL-----PA 280

  Fly   141 SSSAL-------ATGWGRGNFLIRPRQLQGVEILIR-PLI---VCKLK--YGNGVFNEDICAGRM 192
            :..||       .||||...:.   .|..||....| |:|   ||...  |||.:..:..||| .
Human   281 AGQALVDGKICTVTGWGNTQYY---GQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAG-Y 341

  Fly   193 GKGG---CYGDSGGPLVFNG--------QLVGITS-RTGNIVCLGSSLYASVARYRNWILSAIDV 245
            .:||   |.||||||.|...        :|.||.| .||..:.....:|..|:.:|.||..||..
Human   342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKT 406

  Fly   246 LHFQA 250
             |.:|
Human   407 -HSEA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	87/249 (35%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	94/265 (35%)
		Tryp_SPc	163..400	CDD:238113	86/248 (35%)