Protein Alignment Ser12 and KLK4

DIOPT Version :9

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 79/251 - (31%)
• Similarity: 128/251 - (50%)
• Gaps: 20/251 - (7%)

  Fly     3 LHWLVLVASVTLISAGSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVE 67
            |.:|:|..:.:|:|...|  :|:.|........||||||:...:..|..|:...:.:::||||
Human    12 LGYLILGVAGSLVSGSCS--QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC-- 72

  Fly    68 RPFDTLYSVRVG----SVWKNLGGQHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRP 128
              |...|::.:|    ...:..|.|....::..:|.:| :..:|.||:.:|:|.:::..:..:|.
Human    73 --FQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEY-NRPLLANDLMLIKLDESVSESDTIRS 134

  Fly   129 IQLADSAPAAGTEASVSGWGEI--GILWLQPTSLLKTSVKILDPNVCKRSYQYI-TKTMICAAA- 189
            |.:|...|.||....|||||.:  |.:   ||.|...:|.::...||.:.|..: ..:|.||..
Human   135 ISIASQCPTAGNSCLVSGWGLLANGRM---PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG 196

  Fly   190 -LLKDSCHGDSGGPLVSGGQLVGIVSYG-IGCANPFFPGVYANVAELKPWILNAIE 243
             ..||||:|||||||:..|.|.|:||:| ..|.....||||.|:.:...||...::
Human   197 QDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	71/224 (32%)
		Tryp_SPc	24..238	CDD:238113	71/223 (32%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	73/226 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920