Protein Alignment Ser12 and PRSS27

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 84/251 - (33%)
• Similarity: 119/251 - (47%)
• Gaps: 33/251 - (13%)

  Fly    23 RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPFDT-LYSVRVGSVWKNLG 86
            |:|||......|.|||.::..:..:.||..:.:::.::|||||.....:| ||.|.:|:......
Human    34 RMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQP 98

  Fly    87 GQHARVAVIRKHEDYVSSTILFN------DIAVIRLVDTLIFNAEVRPIQLADSAP--AAGTEAS 143
            |.||..|.:|:    |.|..|:.      |:|::.|...:.|...:.|:.|.|.:.  ..|....
Human    99 GPHAMYARVRQ----VESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCW 159

  Fly   144 VSGWG---EIGILWLQPTSLLKTSVKILDPNVCKRSYQ------YITKT----MICAA--ALLKD 193
            |:|||   |..:| .:|..|.|.:|.|:|...|...|.      |..||    |:||.  ...||
Human   160 VTGWGSPSEEDLL-PEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKD 223

  Fly   194 SCHGDSGGPLVS-GGQ---LVGIVSYGIGCANPFFPGVYANVAELKPWILNAIEQL 245
            :|.||||||||. .||   ..|::|:|.|||....||||..|.....||...|.:|
Human   224 ACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKL 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	80/242 (33%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	81/243 (33%)