Protein Alignment Ser12 and Tmprss5

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_001346389.1
• Gene: Tmprss5 / 80893
• MGIID: 1933407
• Length: 455
• Species: Mus musculus
• Alignment Length: 270
• Identity: 92/270 - (34%)
• Similarity: 133/270 - (49%)
• Gaps: 52/270 - (19%)

  Fly     9 VASVTLISAGSSP--ERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPFD 71
            :.|:.....|:.|  .|||||..|.....||||::|...::.|||.:.:...::|||||
Mouse   201 IVSLKCSECGARPLASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPHWVVTAAHC------ 259

  Fly    72 TLYSVRVG--SVWKNLGGQHARVAVIRKHEDYVSSTILFN----------DIAVIRLVDTLIFNA 124
             :||.|:.  |.|:...|..:..|| |:|:..:...|:.:          |:|:::|...:.|:.
Mouse   260 -MYSFRLSRLSSWRVHAGLVSHGAV-RQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSD 322

  Fly   125 EVRPIQLADSAPAA------GTEASVSGWGEIGILWLQPT------SLLKTSVKILDPNVCKRSY 177
            .|..:.|    ||.      |::..|||||.     ..|:      :|..|.|.:|...:|..|.
Mouse   323 TVGAVCL----PAKEQHFPWGSQCWVSGWGH-----TDPSHTHSSDTLQDTMVPLLSTYLCNSSC 378

  Fly   178 QY---ITKTMICAAAL--LKDSCHGDSGGPLV--SGG--QLVGIVSYGIGCANPFFPGVYANVAE 233
            .|   :|..|:||..|  ..|:|.||||||||  ||.  .|||:||:|.|||.|..|||||.|||
Mouse   379 MYSGALTHRMLCAGYLDGRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAE 443

  Fly   234 LKPWILNAIE 243
            ...||.:.::
Mouse   444 FLDWIHDTVQ 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	87/247 (35%)
Tmprss5	NP_001346389.1	SRCR_2	116..213	CDD:464747	2/11 (18%)
		Tryp_SPc	217..448	CDD:214473	87/247 (35%)