DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser12 and Prss36

DIOPT Version :9

Sequence 1:	NP_523456.1	Gene:	Ser12 / 33406	FlyBaseID:	FBgn0011832	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	251	Identity:	87/251 - (34%)
Similarity:	119/251 - (47%)	Gaps:	38/251 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PE---RIVGG---HPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHC-----VERPFDTLY 74
            ||   |||||   ||   ...|||.:|.....:|||..:.:...:::||||     ...|.|.|
Mouse    42 PEPSSRIVGGSDAHP---GTWPWQVSLHQGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADEL- 102

  Fly    75 SVRVG--SVWKNLGGQHAR-VAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQL--ADS 134
            ||.:|  |....|.|.|.| ||.|...::| |:..|..|:|::||.........|||:.|  |..
Mouse   103 SVLLGVHSQDGPLEGAHMRSVATILIPDNY-STVELGADLALLRLASPAKLGPSVRPVCLPRASH 166

  Fly   135 APAAGTEASVSGWGEI--GILWLQPTSLLKTSVKILDPNVCKRSYQ---------YITKTMICAA 188
            ..|.||....:|||::  .:....|..|.:..:::|....|:..|.         .:...|:||.
Mouse   167 LFAHGTACWATGWGDVQEAVPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAG 231

  Fly   189 --ALLKDSCHGDSGGPLV--SGGQ--LVGIVSYGIGCANPFFPGVYANVAELKPWI 238
              |..:|:|.||||||||  .||:  |.||.|:|.||.....|||:..||..:.||
Mouse   232 YPAGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAPYESWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	83/244 (34%)
Ser12	NP_523456.1	Tryp_SPc	24..238	CDD:238113	82/243 (34%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	84/245 (34%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839462
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030