Protein Alignment Ser12 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 84/279 - (30%)
• Similarity: 127/279 - (45%)
• Gaps: 54/279 - (19%)

  Fly     2 LLHWLVLVASVTLISAGSSP------ER--IVGGHPVLISEVPWQAALMYSEKY---ICGAVIYS 55
            :|:.|:|...|....|.::|      :|  ||||.....|:.|||.:|.....|   .||..:..
Human     1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIH 65

  Fly    56 DKIIITAAHCVERPFDTLYSVRVGSVWKNLGGQH----------ARVAVIRKHEDYVSSTILFND 110
            .:.::||||||......|.::||     .|..||          :|:.|   |..:.::.| ..|
Human    66 PQWVLTAAHCVGPDVKDLAALRV-----QLREQHLYYQDQLLPVSRIIV---HPQFYTAQI-GAD 121

  Fly   111 IAVIRLVDTLIFNAEVRPIQLADSAPAA-----GTEASVSGWGEI--GILWLQPTSLLKTSVKIL 168
            ||::.|.:.:..::.|..:.|   .||:     |....|:|||::  ......|..|.:..|.|:
Human   122 IALLELEEPVNVSSHVHTVTL---PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIM 183

  Fly   169 DPNVCKRSY----------QYITKTMICAAALLKDSCHGDSGGPL---VSGGQL-VGIVSYGIGC 219
            :.::|...|          :.:...|:||....:|||.|||||||   |:|..| .|:||:|.||
Human   184 ENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGC 248

  Fly   220 ANPFFPGVYANVAELKPWI 238
            |.|..||:|..|.....||
Human   249 AQPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	76/250 (30%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	77/249 (31%)