Protein Alignment Ser12 and PRSS56

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 72/230 - (31%)
• Similarity: 107/230 - (46%)
• Gaps: 15/230 - (6%)

  Fly    23 RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHC-VERPFDTLYSVRVGSVWKNLG 86
            |||||........||...|....:.:||.|:.:...::||||| |..|.:.|::|.:....:...
Human   104 RIVGGSAAPPGAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELLWTVTLAEGSRGEQ 168

  Fly    87 GQHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLAD--SAPAAGTEASVSGWGE 149
            .:...|..|..|..:...| ..||:|:::|...:......||:.|..  ..|.|||..:::|||.
Human   169 AEEVPVNRILPHPKFDPRT-FHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGA 232

  Fly   150 IGILWLQPTSLLKTSVKILDPNVCKRSY--QYITKTMICAAALL--KDSCHGDSGGPLVSGGQ-- 208
            :.....:..::.:..|.:|..:.|:|:.  .....||:||..|.  .|||.|||||||.....
Human   233 LFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGP 297

  Fly   209 -----LVGIVSYGIGCANPFFPGVYANVAELKPWI 238
                 |.|:.|:|.||..|..||||..||..|.|:
Human   298 RPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	71/228 (31%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	71/229 (31%)
		PksD	<178..600	CDD:442550	50/156 (32%)