DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser12 and CG17234

DIOPT Version :9

Sequence 1:	NP_523456.1	Gene:	Ser12 / 33406	FlyBaseID:	FBgn0011832	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	101/266 - (37%)
Similarity:	144/266 - (54%)	Gaps:	37/266 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLHWLVLVASVTLISAGSS---PERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITA 62
            |.:...:|:.::..:|||..   .:||:||.|:.|.:||||.:|.|...::||..|||:.||:||
  Fly     1 MFIESFLLLLALDFLSAGQVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTA 65

  Fly    63 AHCV-----ERPFDTLYSVRVGSVWKNLGGQHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIF 122
            |||.     .|..|..|.||.||...:..|....||.:..||:| :..:..||||::||...|.|
  Fly    66 AHCFFDEEGNRLDDQGYQVRAGSALTDSNGTLVDVAALIIHEEY-AFDLNINDIAIVRLSTPLEF 129

  Fly   123 NAEVRPIQLADSAPAAGTEASVSGWGEIGIL----WLQPTSL------LKT--SVKILDPNVCKR 175
            .::|:||.||.:.|...:.|.|||||...||    .|.||.|      :|:  |.::.||
  Fly   130 TSKVQPIPLAKTNPYPRSIALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSCRLFDP----- 189

  Fly   176 SYQYITKTMICAAALLKDSCHGDSGGPLVSGGQLVGIVSYG-IGCANPFFPGVYANVAELKPWIL 239
                   :::||....:.:||||||||||...||||:||:| .||.:..|   :.:|...:.|||
  Fly   190 -------SLLCAGTYGRTACHGDSGGPLVVNKQLVGVVSWGRKGCVSSAF---FVSVPYFREWIL 244

  Fly   240 NAIEQL 245
            |||..:
  Fly   245 NAIASI 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	90/232 (39%)
Ser12	NP_523456.1	Tryp_SPc	24..238	CDD:238113	89/231 (39%)
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	90/232 (39%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	89/231 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443134
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	1	1.000	-	-		FOG0000678
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850