DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ser12 and Klk4

DIOPT Version :9

Sequence 1:NP_523456.1 Gene:Ser12 / 33406 FlyBaseID:FBgn0011832 Length:245 Species:Drosophila melanogaster
Sequence 2:NP_064312.1 Gene:Klk4 / 56640 MGIID:1861379 Length:255 Species:Mus musculus


Alignment Length:255 Identity:80/255 - (31%)
Similarity:123/255 - (48%) Gaps:28/255 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 WLV--LVASVTLISAGSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVE 67
            |.:  |:..||..||.|...||:.|........||||||...:.:.|..|:...:.:::||||::
Mouse    11 WFLGCLILEVTGASASSVSSRIIQGQDCSPHSQPWQAALFSEDGFFCSGVLVHPQWVLSAAHCLQ 75

  Fly    68 RPFDTLYSVRVGSVWKNLGGQ--------HARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNA 124
            .      |..||....||.|.        .|.:::  :|.:: :.....||:.:|:|.:::|.:.
Mouse    76 E------SYIVGLGLHNLKGSQEPGSRMLEAHLSI--QHPNF-NDPSFANDLMLIKLNESVIESN 131

  Fly   125 EVRPIQLADSAPAAGTEASVSGWGEI--GILWLQPTSLLKTSVKILDPNVCKRSYQYITK-TMIC 186
            .:|.|.:|...|..|....|||||::  |.|   |:.|...::.:.....|:..|..:.. :|.|
Mouse   132 TIRSIPVATQCPTPGDTCLVSGWGQLKNGKL---PSLLQCVNLSVASEETCRLLYDPVYHLSMFC 193

  Fly   187 AAA--LLKDSCHGDSGGPLVSGGQLVGIVSYGIG-CANPFFPGVYANVAELKPWILNAIE 243
            |..  ..||||:||||||:|....|.|:||.|.| |..|..|.||.|:.:...||...|:
Mouse   194 AGGGQDQKDSCNGDSGGPIVCNRSLQGLVSMGQGKCGQPGIPSVYTNLCKFTNWIQTIIQ 253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ser12NP_523456.1 Tryp_SPc 23..238 CDD:214473 70/228 (31%)
Tryp_SPc 24..238 CDD:238113 69/227 (30%)
Klk4NP_064312.1 Tryp_SPc 32..251 CDD:238113 71/230 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 156 1.000 Domainoid score I4174
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

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