Protein Alignment Ser12 and PRSS3

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 90/230 - (39%)
• Similarity: 119/230 - (51%)
• Gaps: 17/230 - (7%)

  Fly    22 ERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPFDTLYSVRVGS-VWKNL 85
            ::||||:....:.:|:|.:| .|..:.||..:.|::.:::||||    :.|...||:|. ..|.|
Human    36 DKIVGGYTCEENSLPYQVSL-NSGSHFCGGSLISEQWVVSAAHC----YKTRIQVRLGEHNIKVL 95

  Fly    86 GG--QHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLADSAPAAGTEASVSGWG 148
            .|  |....|.|.:|..|...| |.|||.:|:|....:.||.|..|.|..:.||||||..:||||
Human    96 EGNEQFINAAKIIRHPKYNRDT-LDNDIMLIKLSSPAVINARVSTISLPTTPPAAGTECLISGWG 159

  Fly   149 ---EIGILWLQPTSLLKTSVKILDPNVCKRSYQ-YITKTMICAAALL--KDSCHGDSGGPLVSGG 207
               ..|..:  |..|......:|....||.||. .||.:|.|...|.  ||||..|||||:|..|
Human   160 NTLSFGADY--PDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNG 222

  Fly   208 QLVGIVSYGIGCANPFFPGVYANVAELKPWILNAI 242
            ||.|:||:|.|||....||||..|.....||.:.|
Human   223 QLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	87/223 (39%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	89/225 (40%)