DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ser12 and PRSS2

DIOPT Version :9

Sequence 1:NP_523456.1 Gene:Ser12 / 33406 FlyBaseID:FBgn0011832 Length:245 Species:Drosophila melanogaster
Sequence 2:NP_001290343.1 Gene:PRSS2 / 5645 HGNCID:9483 Length:261 Species:Homo sapiens


Alignment Length:261 Identity:93/261 - (35%)
Similarity:132/261 - (50%) Gaps:32/261 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LVASVTLISAG-SSP----ERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVE 67
            |:..:|.::|. ::|    ::||||:....:.||:|.:| .|..:.||..:.|::.:::|.||.:
Human     3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSAGHCYK 66

  Fly    68 RPFDTLYS----------VRVGSVWKNL-----GGQHARVAVIRKHEDYVSSTILFNDIAVIRLV 117
            ...::..|          ||:|.  .|:     ..|....|.|.:|..|.|.| |.|||.:|:|.
Human    67 SAINSKLSGRGCEYHRIQVRLGE--HNIEVLEGNEQFINAAKIIRHPKYNSRT-LDNDILLIKLS 128

  Fly   118 DTLIFNAEVRPIQLADSAPAAGTEASVSGWGEI---GILWLQPTSLLKTSVKILDPNVCKRSYQ- 178
            ...:.|:.|..|.|..:.||||||:.:||||..   |..:  |..|......:|....|:.||. 
Human   129 SPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADY--PDELQCLDAPVLSQAECEASYPG 191

  Fly   179 YITKTMICAAALL--KDSCHGDSGGPLVSGGQLVGIVSYGIGCANPFFPGVYANVAELKPWILNA 241
            .||..|.|...|.  ||||.||||||:||.|:|.||||:|.|||....||||..|.....||.:.
Human   192 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDT 256

  Fly   242 I 242
            |
Human   257 I 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ser12NP_523456.1 Tryp_SPc 23..238 CDD:214473 86/235 (37%)
Tryp_SPc 24..238 CDD:238113 86/234 (37%)
PRSS2NP_001290343.1 Tryp_SPc 23..253 CDD:214473 86/235 (37%)
Tryp_SPc 24..256 CDD:238113 88/237 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8646
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

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