Protein Alignment Ser12 and KLK15

DIOPT Version :9

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 89/271 - (32%)
• Similarity: 124/271 - (45%)
• Gaps: 48/271 - (17%)

  Fly     5 WLVLVASVTLIS-AGSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVER 68
            ||:|..|..|.| |....::::.|........|||.||....::.|||.:.|...:::||||..|
Human     2 WLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSR 66

  Fly    69 PFDTLYSVRVG--SVWKNLGGQHARVA--VI-------RKHEDYVSSTILFNDIAVIRLVDTLIF 122
                ...||:|  ::.|..|.:..|..  ||       |.|.         |||.::|||.....
Human    67 ----FMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHR---------NDIMLLRLVQPARL 118

  Fly   123 NAEVRPIQLADSAPAAGTEASVSGWG---------------EIGILWLQPTSLLKTSVKILDPNV 172
            |.:|||..|....|..|....|||||               ::.:    |.:|...::.|:....
Human   119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSL----PDTLHCANISIISDTS 179

  Fly   173 CKRSYQ-YITKTMICAAALLK--DSCHGDSGGPLVSGGQLVGIVSYG-IGCANPFFPGVYANVAE 233
            |.:||. .:|.||:||.|..:  :||.||||||||.||.|.||||:| :.|.|...||||..|..
Human   180 CDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCH 244

  Fly   234 LKPWILNAIEQ 244
            ...||...:::
Human   245 YLEWIRETMKR 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	80/244 (33%)
		Tryp_SPc	24..238	CDD:238113	80/243 (33%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	80/240 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8646
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920