DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser12 and Prss36

DIOPT Version :9

Sequence 1:	NP_523456.1	Gene:	Ser12 / 33406	FlyBaseID:	FBgn0011832	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	81/258 - (31%)
Similarity:	117/258 - (45%)	Gaps:	52/258 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PE---RIVGG---HPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPFDTLYSVRVG 79
            ||   |||||   ||   ...|||.:|.:...:|||..:.:...:::||||    |.|..::...
  Rat    53 PEPSSRIVGGSDAHP---GTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHC----FVTNGTLEPA 110

  Fly    80 SVWKNLGGQHAR-----------VAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQL-- 131
            ..|..|.|.|::           ||.|...::| |...|..|:|::||.........|:|:.|
  Rat   111 DEWSVLLGVHSQDGPLEGAHMRSVATILVPDNY-SRVELGADLALLRLASPAKLGPSVKPVCLPR 174

  Fly   132 ADSAPAAGTEASVSGWGEI------GILWLQPTSLLKTSVKILDPNVCKRSYQ---------YIT 181
            |....|.||....:|||::      .:.|:    |.:..:|:|....|:..|.         .:.
  Rat   175 ASHLFAHGTACWATGWGDVQESDPLPVPWV----LQEVELKLLGETACQCLYSRPGPFNLTLQLL 235

  Fly   182 KTMICAA--ALLKDSCHGDSGGPLV--SGGQ--LVGIVSYGIGCANPFFPGVYANVAELKPWI 238
            ..|:||.  ...:|:|.||||||||  .||:  |.||.|:|.||.....|||:..||..:.||
  Rat   236 PGMLCAGYPEGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAHYESWI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	77/251 (31%)
Ser12	NP_523456.1	Tryp_SPc	24..238	CDD:238113	76/250 (30%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	78/252 (31%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343281
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940