Protein Alignment Ser12 and CTRB2

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_001020371.3
• Gene: CTRB2 / 440387
• HGNCID: 2522
• Length: 263
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 86/258 - (33%)
• Similarity: 129/258 - (50%)
• Gaps: 27/258 - (10%)

  Fly     1 MLLHWLVL-------VASVTLISAGSSPERIVGGHPVLISEVPWQAALMYSEK---YICGAVIYS 55
            :|..|.:|       |.::..:.:|.|  |||.|...:....|||.:|  .:|   :.||..:.|
Human     6 LLSCWALLGTTFGCGVPAIHPVLSGLS--RIVNGEDAVPGSWPWQVSL--QDKTGFHFCGGSLIS 66

  Fly    56 DKIIITAAHCVERPFDTLYSVRV--GSVWKNLGGQHARVAVIRKHEDYVSSTILFNDIAVIRLVD 118
            :..::|||||..|..|.:.:...  ||..:|:  |..::|.:.|:..:...|: .|||.:::|..
Human    67 EDWVVTAAHCGVRTSDVVVAGEFDQGSDEENI--QVLKIAKVFKNPKFSILTV-NNDITLLKLAT 128

  Fly   119 TLIFNAEVRPIQL--ADSAPAAGTEASVSGWGEIGI-LWLQPTSLLKTSVKILDPNVCKRSY-QY 179
            ...|:..|..:.|  ||....|||..:.:|||:... ....|..|.:.::.:|....||:|: :.
Human   129 PARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRR 193

  Fly   180 ITKTMICAAALLKDSCHGDSGGPLV----SGGQLVGIVSYGIGCANPFFPGVYANVAELKPWI 238
            ||..||||.|....||.||||||||    ....||||||:|....:...|.|||.||:|.||:
Human   194 ITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSRTCSTTTPAVYARVAKLIPWV 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	79/227 (35%)
CTRB2	NP_001020371.3	Tryp_SPc	34..259	CDD:238113	79/228 (35%)