Protein Alignment Ser12 and KLK12

DIOPT Version :9

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 78/242 - (32%)
• Similarity: 119/242 - (49%)
• Gaps: 28/242 - (11%)

  Fly     6 LVLVASVTLISAGSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPF 70
            :.|:..|..:|..::| :|..|.....:..|||..|.......||.|:...:.::|||||    .
Human     5 IFLLLCVLGLSQAATP-KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC----S 64

  Fly    71 DTLYSVRVGS------VWKNLGGQHARVAVIRKHEDYV-SSTILFNDIAVIRLVDTLIFNAEVRP 128
            .:.|.||:|.      .|.. ..:|:..:|  .|..|: :||...:|:.::||...:...:.|:|
Human    65 GSRYWVRLGEHSLSQLDWTE-QIRHSGFSV--THPGYLGASTSHEHDLRLLRLRLPVRVTSSVQP 126

  Fly   129 IQLADSAPAAGTEASVSGWGEIGILWLQPTS----LLK-TSVKILDPNVCKRSYQ-YITKTMICA 187
            :.|.:....||||..|||||    :...|.:    ||: .::.|:....|...|. .||..|:||
Human   127 LPLPNDCATAGTECHVSGWG----ITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCA 187

  Fly   188 AALL-KDSCHGDSGGPLVSGGQLVGIVSYG-IG-CANPFFPGVYANV 231
            ..:. :|:|.||||||||.||.|.|:||:| :| |.....||||..:
Human   188 GGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	74/225 (33%)
		Tryp_SPc	24..238	CDD:238113	74/224 (33%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	74/225 (33%)
		Tryp_SPc	22..236	CDD:238113	74/224 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920