Protein Alignment Ser12 and KLK14

DIOPT Version :9

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_001298111.2
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 92/249 - (36%)
• Similarity: 133/249 - (53%)
• Gaps: 19/249 - (7%)

  Fly     2 LLHWLVLVASVTLISAGSSPERIVGGHPVLISEVPWQAALMYS--EKYICGAVIYSDKIIITAAH 64
            ||...:.|.::.:..:.....:|:|||....|..||||||:..  .:::||..:.|.:.:|||||
Human     3 LLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAH 67

  Fly    65 CVERPFDTLYSVRVGSVWKNLGGQHARVAVIR-----KHEDYVSSTILFNDIAVIRLVDTLIFNA 124
            | .||   :..|.:|.  .||....|...|:|     .|.:|.|.| ..||:.:::|........
Human    68 C-GRP---ILQVALGK--HNLRRWEATQQVLRVVRQVTHPNYNSRT-HDNDLMLLQLQQPARIGR 125

  Fly   125 EVRPIQLADSAPAAGTEASVSGWGEIGI-LWLQPTSLLKTSVKILDPNVCKRSY-QYITKTMICA 187
            .||||::..:..:.||...|||||.|.. :...|.||...::.|....||:::| :.||..|:||
Human   126 AVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCA 190

  Fly   188 AALL--KDSCHGDSGGPLVSGGQLVGIVSYGI-GCANPFFPGVYANVAELKPWI 238
            ....  ||||.||||||||..|||.|:||:|: .||.|.:||||.|:.:.:.||
Human   191 GVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWI 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	87/226 (38%)
		Tryp_SPc	24..238	CDD:238113	87/225 (39%)
KLK14	NP_001298111.2	Tryp_SPc	25..247	CDD:238113	89/227 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8646
orthoMCL	1	0.900	-	-		OOG6_128159
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810