DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser12 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_523456.1	Gene:	Ser12 / 33406	FlyBaseID:	FBgn0011832	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	86/231 - (37%)
Similarity:	113/231 - (48%)	Gaps:	19/231 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVER---PFDTLYSVRVGSVWKN 84
            ::.||......|.||||:|..:..:.|||.:.|:..:||||||..|   |.|  :.|..|.:...
  Rat   186 KVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFVRSANPKD--WKVSFGFLLSK 248

  Fly    85 LGGQHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLADSAP--AAGTEASVSGW 147
            ...|.| |..|..||:| |.....|||||:||...:::...:|...|.::..  ...::..|:||
  Rat   249 PQAQRA-VKSIVIHENY-SYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVTGW 311

  Fly   148 GEIGILWLQPTSLLKTSVKILDPNVCKRSYQY---ITKTMICAAAL--LKDSCHGDSGGPLVSGG 207
            |.:......|..|.|..|||:|...|.....|   ||..|:||..|  ..|:|.|||||||||..
  Rat   312 GTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGPLVSED 376

  Fly   208 Q-----LVGIVSYGIGCANPFFPGVYANVAELKPWI 238
            .     |.||||:|..||.|..||||..|...:.||
  Rat   377 SKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	84/229 (37%)
Ser12	NP_523456.1	Tryp_SPc	24..238	CDD:238113	84/228 (37%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	84/229 (37%)
		Tryp_SPc	187..415	CDD:238113	86/230 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920