Protein Alignment Ser12 and PRSS57

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_999875.2
• Gene: PRSS57 / 400668
• HGNCID: 31397
• Length: 283
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 79/264 - (29%)
• Similarity: 126/264 - (47%)
• Gaps: 36/264 - (13%)

  Fly     6 LVLVASVTLI----SAGSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCV 66
            |:.||:..::    .|||...:|:|||.|.....|:.|::.:..::.||..:...:.:::||||.
Human    12 LLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCF 76

  Fly    67 ERPFDTLYSVRVGSVWKNLGGQHA-----------RVAVIRKHEDYVSSTILFNDIAVIRLVDTL 120
            ..     ..:|.|.|   :.|.|.           .:..:..|.||...|.. |||.::||..:.
Human    77 SH-----RDLRTGLV---VLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHA-NDICLLRLNGSA 132

  Fly   121 IFNAEV---RPIQLADSAPAAGTEASVSGWGEIGILWLQPTSLLKTSVKILDPNVCKRSYQ-YIT 181
            :....|   ||.......|.|||...|:|||.:......|..|::..|::|||:||..|:: ::|
Human   133 VLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLT 197

  Fly   182 KTMICAAALLKDS-----CHGDSGGPLVSGGQLVGIVSY-GIGCANPFFPGVYANVAELKPWILN 240
            .||:|..:  .||     |..|||||||...:..|:||: |:.|.:|..|.||..|:....||.:
Human   198 LTMLCTRS--GDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260

  Fly   241 AIEQ 244
            .:.:
Human   261 VVRR 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	71/235 (30%)
PRSS57	NP_999875.2	Tryp_SPc	34..258	CDD:238113	71/234 (30%)