Protein Alignment Ser12 and Prss21

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: XP_006245934.1
• Gene: Prss21 / 353251
• RGDID: 727870
• Length: 337
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 93/298 - (31%)
• Similarity: 137/298 - (45%)
• Gaps: 73/298 - (24%)

  Fly     6 LVLVASVTLISAGSS--------------------------PERIVGGHPVLISEVPWQAALMYS 44
            :|:...|||.|..|.                          |.|||||....:...|||.:|...
  Rat    14 VVVAVEVTLQSTSSHVKPVDPEKPELQEANLLSGPCGHRTIPSRIVGGEEAELGRWPWQGSLRVW 78

  Fly    45 EKYICGAVIYSDKIIITAAHCVER---PFDTLYSVRVG------SVWKNLGGQHARVAVIRKHED 100
            ..::|||.:.:.:.::|||||.::   |||  ::|:.|      |:| ||.....|..:    ||
  Rat    79 GNHLCGATLLNRRWVLTAAHCFQKDNDPFD--WTVQFGELTSRPSLW-NLQAYSNRYQI----ED 136

  Fly   101 YVSS---TILF-NDIAVIRLVDTLIFNAEVRPIQLADSAP--AAGTEASVSGWGEIG---ILWLQ 156
            ...|   |..| :|||:::|...:.::..::||.|.:|..  |..|:..|:|||.||   .|.|
  Rat   137 IFLSPKYTEQFPHDIALLKLSSPVTYSNFIQPICLLNSTYKFANRTDCWVTGWGAIGEDESLPL- 200

  Fly   157 PTSLLKTSVKILDPNVCKRSYQ------YITKTMICAAALL--KDSC---------HGDSGGPLV 204
            |.:|.:..|.|::..:|...::      .|...|:||.:..  ||:|         .||||||||
  Rat   201 PNNLQEVQVAIINNTMCNHLFKKPDFRINIWGDMVCAGSPEGGKDACFAKLTYAAPQGDSGGPLV 265

  Fly   205 SGGQL----VGIVSYGIGCANPFFPGVYANVAELKPWI 238
            .....    ||:||:||||..|..||||.|::....||
  Rat   266 CNQDTVWYQVGVVSWGIGCGRPNRPGVYTNISHHYNWI 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	84/253 (33%)
Prss21	XP_006245934.1	Tryp_SPc	57..303	CDD:214473	84/253 (33%)