DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser12 and Send2

DIOPT Version :9

Sequence 1:	NP_523456.1	Gene:	Ser12 / 33406	FlyBaseID:	FBgn0011832	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_609708.2	Gene:	Send2 / 34836	FlyBaseID:	FBgn0264253	Length:	239	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	101/250 - (40%)
Similarity:	137/250 - (54%)	Gaps:	23/250 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLHWLVLVASVTLISAG---SSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITA 62
            |.:...:|:.::..:|||   ...|||:||.|:.|.|.|||.::....|::||..|||..|||||
  Fly     1 MFIQSFLLLLALNSLSAGPVIRPEERIIGGQPIGIEEAPWQVSIQRDGKHLCGGSIYSADIIITA 65

  Fly    63 AHCVERPFDTLYSVRVGSVWKNLGGQHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVR 127
            ||||:   ...|.||.||..||..|....||.||.||.      |.||||::||...|.|..:|:
  Fly    66 AHCVQ---GQGYQVRAGSALKNSNGSVVDVAAIRTHEG------LGNDIAIVRLSKPLEFTNQVQ 121

  Fly   128 PIQLADSAPAAGTEASVSGWGEIGILWLQPTSLLKTSVKILDPNVCKRSYQYITK-TMICAAALL 191
            ||.||.:.|..|:.|.|||||. ...:..|..|...::.|..|..|.     :|: :.|||.:..
  Fly   122 PIPLAKTNPPPGSIAFVSGWGS-SSYYSHPIDLQGVNLYIQWPYYCG-----LTEPSRICAGSFG 180

  Fly   192 KDSCHGDSGGPLVSGGQLVGIVSYGI-GCANPFFPGVYANVAELKPWILNAIEQL 245
            :.:|.||||||||...||||:||.|. .|.   :..:|.:|...:.||||||:::
  Fly   181 RAACKGDSGGPLVFDQQLVGVVSGGTKDCT---YSSIYTSVPYFREWILNAIDEI 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	89/216 (41%)
Ser12	NP_523456.1	Tryp_SPc	24..238	CDD:238113	88/215 (41%)
Send2	NP_609708.2	Tryp_SPc	26..225	CDD:214473	89/216 (41%)
Send2	NP_609708.2	Tryp_SPc	27..225	CDD:238113	88/215 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25744
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000678
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020