Protein Alignment Ser12 and PRSS48

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 80/268 - (29%)
• Similarity: 130/268 - (48%)
• Gaps: 50/268 - (18%)

  Fly     6 LVLVASVTLISAGSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPF 70
            |:|:..:::........|:|||........|||.:|.:...:|||..:.|:::|:|||||::..:
Human    10 LLLLLGISVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTW 74

  Fly    71 DTL-YSVRVGSVWKNLGGQHAR----VAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQ 130
            .|. |:|.:||:  .:|....|    |:.|..|..|..:|.   |:|:::|...:.|.:.:.||.
Human    75 TTFSYTVWLGSI--TVGDSRKRVKYYVSKIVIHPKYQDTTA---DVALLKLSSQVTFTSAILPIC 134

  Fly   131 LADSAPAAGTEAS------VSGWGEIGILWLQPTS-------LLKTSVKILDPNVCKRSYQ---- 178
            |    |:...:.:      |:|||::     :.:|       |.:..|.|:|...|::.|.
Human   135 L----PSVTKQLAIPPFCWVTGWGKV-----KESSDRDYHSALQEAEVPIIDRQACEQLYNPIGI 190

  Fly   179 -------YITKTMICAAAL--LKDSCHGDSGGPL---VSGGQL-VGIVSYGIGCANPFFPGVYAN 230
                   .|.:..|||...  :||||.|||||||   :.|..: .|:||:|:.|... .||||.|
Human   191 FLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGKS-LPGVYTN 254

  Fly   231 VAELKPWI 238
            |...:.||
Human   255 VIYYQKWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	76/249 (31%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	77/250 (31%)