Protein Alignment Ser12 and PRSS38

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_898885.1
• Gene: PRSS38 / 339501
• HGNCID: 29625
• Length: 326
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 76/237 - (32%)
• Similarity: 121/237 - (51%)
• Gaps: 18/237 - (7%)

  Fly    23 RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPFD-TLYSVRVGSVWKNLG 86
            :|:||.|....:.|||.::.|:..::||..|.::..:::||||..|..: .:|.:.||.|...:.
Human    59 KILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVA 123

  Fly    87 GQHARVAVIRK---HEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLADSAPAAG-TEAS--VS 145
            |.|.:...:.:   |..|.....:..|:|:::|...::|:..|.|:.||  .|... |.|:  .:
Human   124 GNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLA--TPEVNLTSANCWAT 186

  Fly   146 GWGEIGILWLQPTSLLKTSVKILDPNVCKRSY---QYITKTMICAAALL--KDSCHGDSGGPLV- 204
            |||.:.........|.:..:.::....|...|   .||...|:||..:|  |..|.||||||||
Human   187 GWGLVSKQGETSDELQEMQLPLILEPWCHLLYGHMSYIMPDMLCAGDILNAKTVCEGDSGGPLVC 251

  Fly   205 ---SGGQLVGIVSYGIGCANPFFPGVYANVAELKPWILNAIE 243
               .....:||||:|.||:||.:|||||:|:....||.:.||
Human   252 EFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNIE 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	72/230 (31%)
PRSS38	NP_898885.1	Tryp_SPc	60..291	CDD:238113	74/232 (32%)