Protein Alignment Ser12 and Prss22

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_001100454.1
• Gene: Prss22 / 302971
• RGDID: 1310880
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 271
• Identity: 88/271 - (32%)
• Similarity: 139/271 - (51%)
• Gaps: 34/271 - (12%)

  Fly     6 LVLVASVTLISAGS---SPE--------RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKII 59
            |||:.|...:||.:   ||:        |:|||.....::.||..:::.:..:.|...:.:::.:
  Rat    21 LVLLTSTATVSAANIRGSPDCGKPQQLNRVVGGEDSADAQWPWIVSILKNGSHHCAGSLLTNRWV 85

  Fly    60 ITAAHCVERPFD--TLYSVRVGSVWK--NLG--GQHARVAVIRKHEDYVSSTILFNDIAVIRLVD 118
            ::||||.....|  :.|||.:|: ||  |.|  .|...:|.:..|..|........|||::||..
  Rat    86 VSAAHCFSSNMDKPSPYSVLLGA-WKLGNPGPRSQKVGIASVLPHPRYSRKEGTHADIALVRLER 149

  Fly   119 TLIFNAEVRPIQLADSAP--AAGTEASVSGWGEI--GILWLQPTSLLKTSVKILDPNVCKRSY-- 177
            .:.|:..:.||.|.||:.  ...|...::|||.|  |:...:|.:|.|..|.|:||.:||..|
  Rat   150 PIQFSERILPICLPDSSVHLPPNTNCWIAGWGSIQDGVPLPRPQTLQKLKVPIIDPELCKSLYWR 214

  Fly   178 ----QYITKTMICAAAL--LKDSCHGDSGGPLV----SGGQLVGIVSYGIGCANPFFPGVYANVA 232
                :.||:.|:||..|  .:|:|.|||||||:    ....|.||:|:|.|||....||||.::.
  Rat   215 GAGQEAITEDMLCAGYLEGKRDACLGDSGGPLMCQVDDHWLLTGIISWGEGCAERNRPGVYTSLL 279

  Fly   233 ELKPWILNAIE 243
            ..:||:...::
  Rat   280 AHRPWVQRIVQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	79/236 (33%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	79/238 (33%)