Protein Alignment Ser12 and GZMM

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 80/248 - (32%)
• Similarity: 128/248 - (51%)
• Gaps: 22/248 - (8%)

  Fly     7 VLVASVTLISAGSS-PERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPF 70
            :||.::..:|.||| ..:|:||..|:....|:.|:|..:..::||.|:...|.::|||||:.:..
Human     8 LLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRM 72

  Fly    71 DTLYSVRVGSVWKNLGGQ--HARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLAD 133
            ..|..| :|....:..|.  |.:.|:  :|..|.....|.||:|:::|...:..:..:||:.|..
Human    73 AQLRLV-LGLHTLDSPGLTFHIKAAI--QHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPS 134

  Fly   134 --SAPAAGTEASVSGWG---EIGILWLQPTSLLKTSVKILDPNVCKRSYQY---ITKTMICAAAL 190
              ...||||..|::|||   :.|.|   ...|.:..:::||..:|..|..:   ::.:|:|.||.
Human   135 KRQVVAAGTRCSMAGWGLTHQGGRL---SRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAAD 196

  Fly   191 LKDS--CHGDSGGPLVSG-GQ-LVGIVSYGIG-CANPFFPGVYANVAELKPWI 238
            .||.  |.||||||||.| |: |..::|:... |.:.|.|.|...||....||
Human   197 SKDQAPCKGDSGGPLVCGKGRVLARVLSFSSRVCTDIFKPPVATAVAPYVSWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	72/229 (31%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	74/230 (32%)